Department of Radiation Oncology, Stanford university, Palo Alto, CA, 94304, USA.
J Appl Clin Med Phys. 2020 Mar;21(3):162-166. doi: 10.1002/acm2.12842. Epub 2020 Feb 28.
As C-arm linac radiation therapy evolves toward faster, more efficient delivery, and more conformal dosimetry, treatments with increasingly complex couch motions are emerging. Monitoring the patient motion independently of the couch motion during non-coplanar, non-isocentric, or dynamic couch treatments is a key bottleneck to their clinical implementation. The goal of this study is to develop a prototype real-time monitoring system for unconventional beam trajectories to ensure a safe and accurate treatment delivery.
An in-house algorithm was developed for tracking using a couch-mounted three-dimensional (3D) depth camera. The accuracy of patient motion detection on the couch was tested on a 3D printed phantom created from the body surface contour exported from the treatment planning system. The technique was evaluated against a commercial optical surface monitoring system with known phantom displacements of 3, 5, and 7 mm in lateral, longitudinal, and vertical directions by placing a head phantom on a dynamic platform on the treatment couch. The stability of the monitoring system was evaluated during dynamic couch trajectories, at speeds between 10.6 and 65 cm/min.
The proposed monitoring system agreed with the ceiling mounted optical surface monitoring system in longitudinal, lateral, and vertical directions within 0.5 mm. The uncertainty caused by couch vibration increased with couch speed but remained sub-millimeter for speeds up to 32 cm/min. For couch speeds of 10.6, 32.2, and 65 cm/min, the uncertainty ranges were 0.27- 0.73 mm, 0.15-0.87 mm, and 0.28-1.29 mm, respectively.
By mounting a 3D camera in the same frame-of-reference as the patient and eliminating dead spots, this proof of concept demonstrates real-time patient monitoring during couch motion. For treatments with non-coplanar beams, multiple isocenters, or dynamic couch motion, this provides additional safety without additional radiation dose and avoids some of the complexity and limitations of room mounted systems.
随着 C 臂直线加速器放射治疗向更快速、更高效、更适形剂量学方向发展,越来越复杂的治疗床运动的治疗方案开始出现。在非共面、非等中心或动态治疗床治疗中,独立于治疗床运动监测患者运动是其临床应用的关键瓶颈。本研究的目的是开发一种用于非常规射束轨迹的实时监测系统,以确保安全、准确的治疗实施。
开发了一种用于使用安装在治疗床上的三维(3D)深度相机进行跟踪的内部算法。使用从治疗计划系统导出的体表面轮廓创建的 3D 打印体模测试了治疗床上患者运动检测的准确性。通过将头部体模放置在治疗床上的动态平台上,使用具有已知体模位移的商业光学表面监测系统,在横向、纵向和垂直方向上分别为 3、5 和 7mm,对该技术进行了评估。在速度为 10.6 至 65cm/min 之间的动态治疗床轨迹期间评估了监测系统的稳定性。
所提出的监测系统在纵向、横向和垂直方向上与天花板安装的光学表面监测系统的误差在 0.5mm 以内。由于治疗床振动引起的不确定性随治疗床速度增加,但在速度高达 32cm/min 时仍保持在亚毫米范围内。对于治疗床速度为 10.6、32.2 和 65cm/min,不确定度范围分别为 0.27-0.73mm、0.15-0.87mm 和 0.28-1.29mm。
通过在与患者相同的参考框架中安装 3D 相机并消除死角,该概念验证证明了治疗床运动期间的实时患者监测。对于非共面射束、多个等中心或动态治疗床运动的治疗,这提供了额外的安全性,而不会增加额外的辐射剂量,并避免了一些房间安装系统的复杂性和局限性。