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宫颈癌幸存者对绝经和激素治疗的态度和理解。

Cervical cancer survivors' attitudes and understanding of menopause and hormone therapy.

机构信息

Department of Obstetrics and Gynecology, University of Illinois, Chicago, IL.

Survey Research Laboratory, University of Illinois, Chicago, IL.

出版信息

Menopause. 2020 Jun;27(6):701-705. doi: 10.1097/GME.0000000000001520.

Abstract

OBJECTIVE

We designed a survey study to assess the presence and severity of climacteric symptoms, in addition to better understand patients' knowledge and understanding of hormone therapy (HT).

METHODS

We administered a 23-question survey during a patient's clinic visit or over the phone. Study enrollment spanned from March, 2019 to May, 2019. The primary outcomes were severity of menopausal symptoms and willingness to try HT, calculated as a summarized overall score. Chi-square and logistic regression were used for analysis.

RESULTS

Our response rate was 38% (n = 34). Our participants were diverse-67% women were black and 21% women were Hispanic. Stage 1 and 2 disease was reported in 32% and 41% of women. Also, 82% and 94% of women reported ever receiving any chemotherapy or radiation therapy. There was no association between willingness to try HT for relief of menopausal symptoms and income (χ [1, 29] = 0.56, P = 0.81) or education level (χ [1, 29] = 2.78, P = 0.10). The most common climacteric symptoms experienced were hot flushes (85%) and decreased libido (77%). Neither symptom severity (odds ratio [OR] 1.31, 95% confidence interval [CI] 0.89-1.94) nor concern for side effects (OR 1.06, 95% CI 0.82-1.36) of HT significantly predicted willingness to try HT.

CONCLUSIONS

Menopausal symptoms were prevalent in this population. Our data indicate that women are experiencing climacteric symptoms, but are overall unmotivated to address symptoms using HT. Factors such as symptom severity, fear of side effects, income level, or education level were not associated with acceptability of HT for premature menopause.

摘要

目的

我们设计了一项调查研究,以评估更年期症状的存在和严重程度,并更好地了解患者对激素治疗(HT)的认识和理解。

方法

我们在患者就诊期间或通过电话进行了一项包含 23 个问题的调查。研究招募时间为 2019 年 3 月至 2019 年 5 月。主要结果是更年期症状的严重程度和尝试 HT 的意愿,计算为综合总评分。采用卡方检验和逻辑回归进行分析。

结果

我们的回复率为 38%(n=34)。我们的参与者多样化,67%的女性是黑人,21%的女性是西班牙裔。32%的女性报告处于疾病 1 期,41%的女性报告处于疾病 2 期。此外,82%和 94%的女性报告曾接受过任何化疗或放疗。尝试 HT 缓解更年期症状的意愿与收入(χ[1,29]=0.56,P=0.81)或教育程度(χ[1,29]=2.78,P=0.10)之间没有关联。经历过的最常见更年期症状是热潮红(85%)和性欲下降(77%)。HT 的症状严重程度(比值比[OR]1.31,95%置信区间[CI]0.89-1.94)或对副作用的担忧(OR 1.06,95%CI 0.82-1.36)均不能显著预测尝试 HT 的意愿。

结论

该人群中更年期症状普遍存在。我们的数据表明,女性正在经历更年期症状,但总体上不愿意使用 HT 来解决这些症状。症状严重程度、对副作用的恐惧、收入水平或教育程度等因素与过早绝经时对 HT 的接受程度无关。

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