Foundation for the Promotion of Health and Biomedical Research of Valencia Region, FISABIO-Public Health, 21, Avenida Catalunya, 46020, Valencia, Spain.
Foundation for the Promotion of Health and Biomedical Research of Valencia Region, FISABIO-Public Health, 21, Avenida Catalunya, 46020, Valencia, Spain; Analytical Chemistry Department, University of Valencia, Edifici Jeroni Muñoz, Dr. Moliner 50, 46100, Burjassot, Spain.
Chemosphere. 2020 Jul;250:126247. doi: 10.1016/j.chemosphere.2020.126247. Epub 2020 Feb 19.
Dietary exposure to polybrominated diphenyl ethers (PBDEs) of the population in the Region of Valencia, Spain, was assessed. A group of 320 composite samples of different fatty foods was collected and analyzed, including the following: vegetable oils, and foods of animal origin such as (a) fish and seafood, (b) eggs, (c) milk and dairy products, and (d) meat and meat products. Two scenarios were assumed for left-censored results: lower-bound (LB) and upper-bound (UB). Vegetable oils, and fish and seafood presented the highest content of PBDEs [mean values of 503 and 464 pg g wet weight (ww) for total PBDEs, respectively, in the UB]. The dominating congeners were BDE47 in the food categories of fish and seafood, meat and meat products, and vegetable oils, and BDE99 in the categories of eggs, and milk and dairy products. The dietary exposure to PBDEs through consumption of the studied foods by the population in the Region of Valencia was estimated for adults (>15 years of age) and young people (6-15 years of age). Average intake levels (UB scenario) were 1.443 and 3.456 ng kg bw day for adults and young people, respectively. In a risk-assessment context, the margin of exposure (MOE) for congener BDE47, -99, -153, and -209 (ranged: 30-3E6) indicate that the current dietary exposure to these substances does not pose a risk to human health.
评估了西班牙巴伦西亚地区人群的多溴二苯醚（PBDEs）饮食暴露情况。采集并分析了 320 个不同脂肪食品的组合样本，包括以下食品：植物油和动物源性食品，如(a)鱼和海鲜、(b)蛋、(c)奶和奶制品以及(d)肉和肉类产品。对于左截断结果，假设了两种情况：下限（LB）和上限（UB）。植物油和鱼及海鲜中 PBDEs 的含量最高[UB 下总 PBDEs 的平均值分别为 503 和 464 pg g 湿重（ww）]。占主导地位的同系物是鱼及海鲜、肉及肉类产品和植物油中的 BDE47，以及蛋类和奶类及奶制品中的 BDE99。通过食用研究食品，估计了巴伦西亚地区成年人（>15 岁）和年轻人（6-15 岁）的 PBDE 饮食暴露量。成人和年轻人的平均摄入量（UB 情景）分别为 1.443 和 3.456 ng kg bw day。在风险评估背景下，BDE47、-99、-153 和 -209 （范围：30-3E6）的暴露量与风险比（MOE）表明，目前这些物质的饮食暴露不会对人类健康构成风险。
