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归因于 PM 导致的北京精神障碍住院的可归因风险和经济成本。

Attributable risk and economic cost of hospital admissions for mental disorders due to PM in Beijing.

机构信息

Department of Occupational and Environmental Health, School of Public Health, Peking University, Beijing 100191, China; Department of Health Policy and Management, Yale School of Public Health, New Haven, CT 06510, United States.

Department of Health Policy and Management, Yale School of Public Health, New Haven, CT 06510, United States; Department of Economics, Yale University, New Haven, CT 06511, United States.

出版信息

Sci Total Environ. 2020 May 20;718:137274. doi: 10.1016/j.scitotenv.2020.137274. Epub 2020 Feb 11.

DOI:10.1016/j.scitotenv.2020.137274
PMID:32109812
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9429815/
Abstract

BACKGROUND

Few studies have estimated the attributable risk and economic cost of mental disorders (MDs) due to particulate matters with aerodynamic diameter of <2.5 μm (PM) exposure in Beijing.

OBJECTIVES

This study aims to identify the possible correlation between PM and risk of hospital admissions (HAs) for MDs in Beijing and calculate the attributable risk and economic cost.

METHODS

A generalized additive model (GAM) with controlling for time trend, meteorological conditions, holidays and day of the week was used to estimate the associations. Stratified analyses were performed by age, gender and season. We further estimated the health and economic burden of HAs for MDs attributable to PM.

FINDINGS

A total of 17,252 HAs for MDs were collected. A 10 μg/m daily increase in PM was associated with a statistically significant risk increase of 3.55% for HAs for MDs. The effects of PM exposures on HAs for MDs were more pronounced in males, elderly (≥65 years old) individuals and in cold seasons. Using WHO's air quality guidelines as the reference, 15.12% of HAs and 16.19% of the related medical expenses for MDs were attributed to PM during the study period.

NOVELTY

PM accounts for substantial morbidity and economic burden of MDs for both the society and households, which shows environmental protections are essential to improve mental health status of the population.

摘要

背景

鲜有研究估计北京地区由于细颗粒物(PM)暴露导致的精神障碍(MDs)的归因风险和经济成本。

目的

本研究旨在确定 PM 与北京 MDs 住院风险之间可能存在的相关性,并计算归因风险和经济成本。

方法

采用广义相加模型(GAM),控制时间趋势、气象条件、节假日和周几,估计相关性。通过年龄、性别和季节进行分层分析。我们进一步估计了归因于 PM 的 MDs 住院的健康和经济负担。

结果

共收集了 17252 例 MDs 住院病例。PM 每日增加 10μg/m 与 MDs 住院风险增加 3.55%具有统计学显著相关性。PM 暴露对 MDs 住院的影响在男性、老年人(≥65 岁)和寒冷季节更为明显。使用世卫组织的空气质量指南作为参考,研究期间,归因于 PM 的 MDs 住院占 15.12%,相关医疗费用占 16.19%。

新颖性

PM 导致了大量 MDs 的发病率和经济负担,无论是对社会还是家庭都是如此,这表明环境保护对于改善人口心理健康状况至关重要。

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