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甲状腺乳头状癌喉前淋巴结转移的临床研究

Clinical Study on Prelaryngeal Lymph Node Metastasis in Papillary Thyroid Carcinoma.

作者信息

Gong Jin-Xing, Gu Jian-Wei, Ji Feng, Li Kun, Zhu Qi, Gu Fang-Ying, Chen Yan, Ji Qing-Hai

机构信息

Department Four of Surgery, Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, People's Republic of China.

Head & Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200000, People's Republic of China.

出版信息

Cancer Manag Res. 2020 Feb 21;12:1323-1327. doi: 10.2147/CMAR.S232884. eCollection 2020.

DOI:10.2147/CMAR.S232884
PMID:32110106
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7041594/
Abstract

OBJECTIVE

This study aims to investigate the risk factors of prelaryngeal lymph node metastasis in papillary thyroid carcinoma and its clinical application value.

METHODS

The clinical pathological features and metastatic risks were statistically analyzed by reviewing 254 patients with papillary thyroid carcinoma, who received their first operation and prelaryngeal lymph node dissection in our department.

RESULTS

The detection of prelaryngeal lymph nodes, tumor size and any paratracheal lymph node metastasis were correlated with the number of paratracheal lymph node metastasis (<0.05), but these were not correlated with age, gender, multiple foci, tumor size, any paratracheal lymph node metastasis, metastatic location, or foci location (>0.05).

CONCLUSION

Paratracheal lymph node metastasis indicates a high possibility of prelaryngeal lymph node metastasis. Paratracheal lymph node dissection combined with prelaryngeal lymph node dissection should be simultaneously considered in operations for thyroid papilla carcinoma.

摘要

目的

本研究旨在探讨甲状腺乳头状癌喉前淋巴结转移的危险因素及其临床应用价值。

方法

回顾性分析254例在我科接受首次手术及喉前淋巴结清扫的甲状腺乳头状癌患者的临床病理特征及转移风险。

结果

喉前淋巴结的检出、肿瘤大小及气管旁淋巴结转移与气管旁淋巴结转移数量相关(<0.05),但与年龄、性别、多灶性、肿瘤大小、气管旁淋巴结转移情况、转移部位或病灶部位无关(>0.05)。

结论

气管旁淋巴结转移提示喉前淋巴结转移可能性大。在甲状腺乳头状癌手术中应同时考虑气管旁淋巴结清扫联合喉前淋巴结清扫。

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Subcategorisation of AUS/FLUS thyroid lesions as per the 2017 Bethesda System for Reporting Thyroid Cytopathology: a retrospective study from a tertiary care centre analysing risk of malignancy (ROM) of the different subcategories.根据 2017 年甲状腺细胞病理学报告的 Bethesda 系统对 AUS/FLUS 甲状腺病变进行分类:来自三级保健中心的回顾性研究,分析不同亚类别的恶性风险(ROM)。
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MKL1 overexpression predicts poor prognosis in patients with papillary thyroid cancer and promotes nodal metastasis.MKL1 过表达预示着甲状腺乳头状癌患者预后不良,并促进淋巴结转移。
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The total number of prelaryngeal and pretracheal lymph node metastases: is it a reliable predictor of contralateral central lymph node metastasis in papillary thyroid carcinoma?喉前及气管前淋巴结转移总数:它是甲状腺乳头状癌对侧中央区淋巴结转移的可靠预测指标吗?
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