Gong Jin-Xing, Gu Jian-Wei, Ji Feng, Li Kun, Zhu Qi, Gu Fang-Ying, Chen Yan, Ji Qing-Hai
Department Four of Surgery, Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, People's Republic of China.
Head & Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai 200000, People's Republic of China.
Cancer Manag Res. 2020 Feb 21;12:1323-1327. doi: 10.2147/CMAR.S232884. eCollection 2020.
This study aims to investigate the risk factors of prelaryngeal lymph node metastasis in papillary thyroid carcinoma and its clinical application value.
The clinical pathological features and metastatic risks were statistically analyzed by reviewing 254 patients with papillary thyroid carcinoma, who received their first operation and prelaryngeal lymph node dissection in our department.
The detection of prelaryngeal lymph nodes, tumor size and any paratracheal lymph node metastasis were correlated with the number of paratracheal lymph node metastasis (<0.05), but these were not correlated with age, gender, multiple foci, tumor size, any paratracheal lymph node metastasis, metastatic location, or foci location (>0.05).
Paratracheal lymph node metastasis indicates a high possibility of prelaryngeal lymph node metastasis. Paratracheal lymph node dissection combined with prelaryngeal lymph node dissection should be simultaneously considered in operations for thyroid papilla carcinoma.
本研究旨在探讨甲状腺乳头状癌喉前淋巴结转移的危险因素及其临床应用价值。
回顾性分析254例在我科接受首次手术及喉前淋巴结清扫的甲状腺乳头状癌患者的临床病理特征及转移风险。
喉前淋巴结的检出、肿瘤大小及气管旁淋巴结转移与气管旁淋巴结转移数量相关(<0.05),但与年龄、性别、多灶性、肿瘤大小、气管旁淋巴结转移情况、转移部位或病灶部位无关(>0.05)。
气管旁淋巴结转移提示喉前淋巴结转移可能性大。在甲状腺乳头状癌手术中应同时考虑气管旁淋巴结清扫联合喉前淋巴结清扫。