沙特阿拉伯王国东部省分离株抗菌药物耐药性增加模式。
Pattern of increased antimicrobial resistance of isolates in the Eastern Province of KSA.
作者信息
Aljindan Reem Y, Alkharsah Khaled R
机构信息
Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University (IAU), Dammam, KSA.
出版信息
J Taibah Univ Med Sci. 2020 Feb 7;15(1):48-53. doi: 10.1016/j.jtumed.2019.12.004. eCollection 2020 Feb.
OBJECTIVES
The antimicrobial resistance of species is increasing worldwide. This study was conducted to determine the pattern of antimicrobial susceptibility of species in a tertiary hospital from 2011 to 2018.
METHODS
In this retrospective study, the medical records of all patients with infections were reviewed. The clinical, demographic, and microbiological data of the selected patients were analysed.
RESULTS
A total of 752 patients were included. The resistance of species to antimicrobial drugs increased from 24.6% in 2011 to 37.8% in 2018 ( = 0.002). By 2018 all isolates were completely resistant to cefalotin, cefuroxime, and cefoxitin, while we found some susceptibility to other cephalosporins and ciprofloxacin. The most commonly isolated serogroups were groups D (36.5%), C (23.5%), and B (11.7%).
CONCLUSIONS
The incidence of resistance of to antibiotics is on the rise. The results of this study highlight the need for an active monitoring system of antibiotic usage in humans and domestic animals.
目的
该物种的抗菌耐药性在全球范围内呈上升趋势。本研究旨在确定2011年至2018年一家三级医院中该物种的抗菌药敏模式。
方法
在这项回顾性研究中，对所有感染该物种的患者的病历进行了审查。对选定患者的临床、人口统计学和微生物学数据进行了分析。
结果
共纳入752例患者。该物种对抗菌药物的耐药性从2011年的24.6%上升至2018年的37.8%（P = 0.002）。到2018年，所有该物种分离株对头孢噻吩、头孢呋辛和头孢西丁完全耐药，而我们发现对其他头孢菌素和环丙沙星有一定敏感性。最常分离出的该物种血清型为D组（36.5%）、C组（23.5%）和B组（11.7%）。
结论
该物种对抗生素的耐药发生率正在上升。本研究结果凸显了对人类和家畜抗生素使用情况建立积极监测系统的必要性。
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