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胃癌临床病理特征与自主神经系统的相关性

Correlations Between Clinicopathological Features and the Vegetative Nervous System in Gastric Cancer.

作者信息

Balea A M, Cruce R, Schenker R A, Ionescu A G, Streba L, Ciurea A M, Ghiluși M C, Pirici D, Vere C E

机构信息

PhD student, University of Medicine and Pharmacy of Craiova, Romania.

Sf. Nectarie Oncology Center, Craiova, Romania.

出版信息

Curr Health Sci J. 2019 Oct-Dec;45(4):351-357. doi: 10.12865/CHSJ.45.04.02. Epub 2019 Dec 30.

Abstract

Gastric cancer currently represents one of the most important public health problems. Recent studies have demonstrated the existence of strong correlations between the vegetative nervous system and the role it plays in the initiation of the oncogenetic process and the progression of cancer. The purpose of this paper is to demonstrate the involvement of the sympathetic and parasympathetic vegetative nervous system in the evolution of gastric cancer, according to the stage of tumor differentiation. In this current paper we have included a number of four patients diagnosed with gastric cancer post UGI (Upper Gastrointestinal Endoscopy) and have analyzed relations that exist between the tumor differentiation degree and the metanephrine and normetanephrine serum level in the blood of the patients. Following the research, we have observed an increased value of the metanephrine and normetanephrine serum level in the patient which displayed the lowest degree of differentiation.

摘要

胃癌目前是最重要的公共卫生问题之一。最近的研究表明,植物神经系统与其在肿瘤发生过程的启动和癌症进展中所起的作用之间存在密切关联。本文的目的是根据肿瘤分化阶段,论证交感和副交感植物神经系统在胃癌发展过程中的参与情况。在本论文中,我们纳入了4例经上消化道内镜检查确诊为胃癌的患者,并分析了患者肿瘤分化程度与血液中变肾上腺素和去甲变肾上腺素血清水平之间的关系。经过研究,我们观察到分化程度最低的患者其变肾上腺素和去甲变肾上腺素血清水平有所升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53d6/7014983/2282ce7a6007/CHSJ-45-4-351-figT.jpg

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