Cassell Ayun, Jalloh Mohamed, Ndoye Medina, Yunusa Bashir, Mbodji Mouhamadou, Diallo Abdourahmane, Gaye Omar, Labou Issa, Niang Lamine, Gueye Serigne
Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.
Department of Surgery, Liberia College of Physicians and Surgeons, Monrovia, Liberia.
Res Rep Urol. 2020 Feb 18;12:35-42. doi: 10.2147/RRU.S242398. eCollection 2020.
Testicular cancer is a common malignancy in young males with higher incidence in developed nations but with the lowest incidence in Africa (0.3-0.6/100 000). Ironically, the global testicular cancer mortality rate has shown a reverse trend to its incidence with higher rates in low- and middle-income countries (0.5 per 100 000) than in high-income countries. Data from GLOBOCAN 2008 have shown relatively high mortality rates in sub-Saharan countries like Mali, Ethiopia, Niger and Malawi. The prognosis of testicular tumor is good with remarkable chemosensitivity to cisplatin-based regimen. Early diagnosis, careful staging and a multidisciplinary management approach is crucial to achieve this optimal result. These results are achievable in the sub-Saharan region if the relevant resources are appropriated for cancer care and clinical guidelines are formulated in a regional context.
睾丸癌是年轻男性中常见的恶性肿瘤，在发达国家发病率较高，但在非洲发病率最低（每10万人中0.3 - 0.6例）。具有讽刺意味的是，全球睾丸癌死亡率呈现出与发病率相反的趋势，低收入和中等收入国家（每10万人中有0.5例）的死亡率高于高收入国家。2008年全球癌症负担数据显示，在撒哈拉以南国家如马里、埃塞俄比亚、尼日尔和马拉维，死亡率相对较高。睾丸肿瘤预后良好，对基于顺铂的治疗方案具有显著的化疗敏感性。早期诊断、仔细分期和多学科管理方法对于实现这一最佳结果至关重要。如果为癌症护理分配相关资源并在区域范围内制定临床指南，在撒哈拉以南地区也可以取得这些成果。
