Nayak Prasanta K, Mitra Subarna, Sahoo Jayaprakash, Mahapatra Eli, Agrawal Sarita, Lone Zamir
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
J Family Med Prim Care. 2020 Jan 28;9(1):147-150. doi: 10.4103/jfmpc.jfmpc_654_19. eCollection 2020 Jan.
To determine the prevalence of obesity and its relationship with subclinical hypothyroidism in women with polycystic ovarian syndrome (PCOS). To compare the clinico-biochemical parameters of obese and lean PCOS patients.
A total of 287 women with PCOS were included in this study after consent. The demographic, anthropometry, clinical, and hormonal (thyroid-stimulating hormone [TSH] and total testosterone) parameters were recorded along with pelvic ultrasonography (USG) for all PCOS subjects. They were divided into lean (body mass index [BMI] between 18.5 and 22.9) and overweight (BMI ≥23), and the number of subclinical hypothyroid patients were calculated in each group. The clinico-biochemical parameters of both groups were compared.
The majority (61%) of our patients were overweight. There was no significant difference in the prevalence of subclinical hypothyroidism between overweight and lean PCOS patients. The obese PCOS patients were older than lean PCOS patients, and they had higher serum testosterone with elevated systolic and diastolic blood pressure (BP).
The majority of our patients were found to be overweight and there was no association between obesity and subclinical hypothyroidism among PCOS patients.
确定多囊卵巢综合征（PCOS）女性中肥胖的患病率及其与亚临床甲状腺功能减退的关系。比较肥胖和非肥胖PCOS患者的临床生化参数。
本研究经同意纳入了287例PCOS女性。记录所有PCOS受试者的人口统计学、人体测量学、临床和激素（促甲状腺激素[TSH]和总睾酮）参数以及盆腔超声检查（USG）结果。将她们分为非肥胖组（体重指数[BMI]在18.5至22.9之间）和超重组（BMI≥23），并计算每组中亚临床甲状腺功能减退患者的数量。比较两组的临床生化参数。
我们的大多数患者（61%）超重。超重和非肥胖PCOS患者中亚临床甲状腺功能减退的患病率无显著差异。肥胖的PCOS患者比非肥胖的PCOS患者年龄更大，血清睾酮水平更高，收缩压和舒张压升高。
我们发现大多数患者超重，且PCOS患者中肥胖与亚临床甲状腺功能减退之间无关联。
