生命起源研究的未来：弥合数十年的分歧。
The Future of Origin of Life Research: Bridging Decades-Old Divisions.
作者信息
Preiner Martina, Asche Silke, Becker Sidney, Betts Holly C, Boniface Adrien, Camprubi Eloi, Chandru Kuhan, Erastova Valentina, Garg Sriram G, Khawaja Nozair, Kostyrka Gladys, Machné Rainer, Moggioli Giacomo, Muchowska Kamila B, Neukirchen Sinje, Peter Benedikt, Pichlhöfer Edith, Radványi Ádám, Rossetto Daniele, Salditt Annalena, Schmelling Nicolas M, Sousa Filipa L, Tria Fernando D K, Vörös Dániel, Xavier Joana C
机构信息
Institute of Molecular Evolution, University of Düsseldorf, 40225 Düsseldorf, Germany.
School of Chemistry, University of Glasgow, Glasgow G128QQ, UK.
出版信息
Life (Basel). 2020 Feb 26;10(3):20. doi: 10.3390/life10030020.
Research on the origin of life is highly heterogeneous. After a peculiar historical development, it still includes strongly opposed views which potentially hinder progress. In the 1st Interdisciplinary Origin of Life Meeting, early-career researchers gathered to explore the commonalities between theories and approaches, critical divergence points, and expectations for the future. We find that even though classical approaches and theories-e.g. bottom-up and top-down, RNA world vs. metabolism-first-have been prevalent in origin of life research, they are ceasing to be mutually exclusive and they can and should feed integrating approaches. Here we focus on pressing questions and recent developments that bridge the classical disciplines and approaches, and highlight expectations for future endeavours in origin of life research.
关于生命起源的研究高度多样化。经过一段独特的历史发展，它仍然包含强烈对立的观点，这可能会阻碍进步。在第一届生命起源跨学科会议上，初出茅庐的研究人员齐聚一堂，探讨理论与方法之间的共性、关键分歧点以及对未来的期望。我们发现，尽管经典的方法和理论——例如自下而上和自上而下、RNA世界与代谢优先——在生命起源研究中一直很普遍，但它们不再相互排斥，而且可以并且应该为整合方法提供支持。在这里，我们关注连接经典学科和方法的紧迫问题和最新进展，并强调对生命起源研究未来努力的期望。
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