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韩国嗅觉障碍的流行病学:一项全国性基于人群的研究。

Epidemiology of Anosmia in South Korea: A Nationwide Population-Based Study.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University School of Medicine, Seoul, Republic of Korea.

Department of Biostatics, Catholic University College of Medicine, Seoul, Republic of Korea.

出版信息

Sci Rep. 2020 Feb 28;10(1):3717. doi: 10.1038/s41598-020-60678-z.

Abstract

Research about the epidemiology of olfactory dysfunction in Asians was not enough. The purpose of this study was to assess the prevalence and incidence rate of olfactory disorders in Koreans and to evaluate demographic risk factors. We analyzed clinical data of patients with anosmia using Korean National Health Insurance Service data from 2006 to 2016. The data includes medical insurance claim data and medical records of almost 50,000,000 people in Korea. The 30-39 age group showed the highest prevalence (19.25 per 10,000 per year). Their incidence rate was also high comparing other age groups (13.30 per 10,000 per year). The prevalence and the incidence increased from 7.10 to 13.74 and from 5.66 to 9.54 between 2006 and 2016. In the seasonal analysis, the incidence rate was high in spring and autumn. The high-income population showed about 1.4-folds higher incidence rate than the low-income population. We thought that the socioeconomic status could generally affect the rate of hospital visit in the anosmia population. Anosmia can be frequently underdiagnosed in the clinical environment because the elderly and the low-income people easily underestimate their anosmia symptom and ignore the severity due to their economic problem. Therefore careful attention and further studies for anosmia are needed.

摘要

亚洲人嗅觉功能障碍的流行病学研究还不够。本研究旨在评估韩国人嗅觉障碍的患病率和发病率,并评估人口统计学危险因素。我们使用韩国国家健康保险服务 2006 年至 2016 年的数据,分析了失嗅患者的临床数据。该数据包括医疗保险索赔数据和近 5000 万人的医疗记录。30-39 岁年龄组的患病率最高(每年每 10000 人 19.25 人)。与其他年龄组相比,其发病率也很高(每年每 10000 人 13.30 人)。2006 年至 2016 年间,患病率和发病率从 7.10 上升到 13.74,从 5.66 上升到 9.54。在季节性分析中,发病率在春季和秋季较高。高收入人群的发病率比低收入人群高约 1.4 倍。我们认为社会经济地位通常会影响失嗅人群的就诊率。在临床环境中,由于老年人和低收入人群容易低估自己的嗅觉障碍症状,并因经济问题而忽视其严重程度,因此失嗅可能经常被误诊。因此,需要对失嗅症进行仔细的关注和进一步的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e7c/7048798/c20ce93d74a6/41598_2020_60678_Fig1_HTML.jpg

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