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波兰激光诊断与治疗中心的光动力诊断和治疗的临床研究与基础研究。

Clinical Trials and Basic Research in Photodynamic Diagnostics and Therapies from the Center for Laser Diagnostics and Therapy in Poland.

机构信息

Department of Internal Medicine, Angiology, and Physical Medicine, Center for Laser Diagnostics and Therapy, Medical University of Silesia in Katowice, Bytom, Poland.

Faculty of Medicine, University of Rzeszów, Rzeszów, Poland.

出版信息

Photochem Photobiol. 2020 May;96(3):539-549. doi: 10.1111/php.13243. Epub 2020 Apr 29.

DOI:10.1111/php.13243
PMID:32112419
Abstract

The purpose of this review is to present an overview of the development of photodiagnostic and photodynamic therapy (PDD and PDT) techniques in Poland. The paper discusses the principles of PDD, including fluorescent techniques in determining precancerous conditions and cancers of the skin, digestive tract, bladder and respiratory tract. Methods of PDT of cancer will be discussed and the current state of knowledge as well as future trends in the development of photodynamic techniques will be presented, including the possibility of using photodynamic antimicrobial therapy. Research pioneers in photodynamic medicine such as Thomas Dougherty are an inspiration for the development of methods of PDD and PDT in our Clinic. The Center for Laser Diagnostics and Therapy in Bytom, Poland, promotes the propagation of PDD and PDT through the training of clinicians and raising awareness among students in training and the general public. Physicians at the Center are engaged in photomedical research aimed at clinical implementation and exploration of new avenues in photomedicine while optimizing existing modalities. The Center promotes dissemination of clinical results from a wide range of topics in PDD and PDT and serving as representative authorities of photodynamic medicine in Poland and Europe.

摘要

本文旨在概述波兰光诊断和光动力疗法(PDD 和 PDT)技术的发展。文中讨论了 PDD 的原理,包括荧光技术在确定癌前病变和皮肤、消化道、膀胱和呼吸道癌症方面的应用。还将讨论 PDT 治疗癌症的方法,并介绍光动力技术的当前知识状况和未来发展趋势,包括光动力抗菌治疗的可能性。光动力医学的研究先驱,如 Thomas Dougherty,为我们诊所的 PDD 和 PDT 方法的发展提供了灵感。波兰比托姆的激光诊断与治疗中心通过培训临床医生和提高培训学生和公众的意识来促进 PDD 和 PDT 的普及。该中心的医生从事光医学研究,旨在将现有模式临床化,并探索光医学的新途径。该中心促进 PDD 和 PDT 广泛领域的临床研究成果的传播,并作为波兰和欧洲光动力医学的权威代表。

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