Institute of Industrial Science (IIS), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan.
Institute of Innovative Research (IIR), Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.
Talanta. 2020 May 15;212:120780. doi: 10.1016/j.talanta.2020.120780. Epub 2020 Jan 23.
Along with the rise of diabetes mellitus issue, glucose sensor has become an imperative tool for healthcare. Studies have been widely conducted on electrode materials for glucose sensors; metal nanoparticles and/or oxide particles in its nano-size are reported to exhibit remarkable electrocatalytic activities in the non-enzymatic glucose sensors. However, the decoration processes of metal nanoparticles or nano-sized oxides are known to be tedious and time-consuming. In addition, the processes usually result in great amount of waste solution emission. In this study, therefore, an Au nanoparticles (NPs)-TiO modified polyaniline (PANI) composite is practiced towards the applications of non-enzymatic glucose sensors, by using a facile and time-saving thermal reduction and by electrodeposition techniques with low waste solution emission. Au NPs, which is modified with TiO nanoparticles in its optimized amount, performs the highest electrocatalytic activity to the oxidation of glucose in alkaline solution. The stability of Au NPs-TiO/PANI is superior to those of most reported results over 70 days. The sensitivity and detection limit are 379.8 μA mM cm and 0.15 μM, respectively. High selectivity of Au NPs-TiO/PANI is also confirmed by the interference test. Spill-over effect of OH between Au NPs and TiO, which is the main reason for the improved catalytic activity, is described in this study.
随着糖尿病问题的出现，葡萄糖传感器已成为医疗保健的必要工具。已经广泛研究了用于葡萄糖传感器的电极材料；据报道，金属纳米粒子和/或纳米尺寸的氧化物具有显著的非酶葡萄糖传感器的电催化活性。然而，众所周知，金属纳米粒子或纳米氧化物的修饰过程繁琐且耗时。此外，这些过程通常会导致大量废溶液的排放。因此，在这项研究中，通过使用简便且省时的热还原和低废溶液排放的电沉积技术，将 Au 纳米粒子（NPs）-TiO 修饰的聚苯胺（PANI）复合材料应用于非酶葡萄糖传感器。在优化量的 TiO 纳米粒子修饰下的 Au NPs 在碱性溶液中对葡萄糖的氧化表现出最高的电催化活性。Au NPs-TiO/PANI 的稳定性优于大多数报道的结果超过 70 天。灵敏度和检测限分别为 379.8 μA mM cm 和 0.15 μM。通过干扰测试也证实了 Au NPs-TiO/PANI 的高选择性。Au NPs 和 TiO 之间的 OH 溢出效应是提高催化活性的主要原因，在本研究中进行了描述。
