Osteoimmunology Lab, Department of Zoology, School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar (MP)-470003, India.
Department of Pharmaceutical Sciences, Dr. Harisingh Gour Central University, Sagar (MP)-470003, India.
Front Biosci (Landmark Ed). 2020 Mar 1;25(7):1259-1296. doi: 10.2741/4855.
Osteoporosis is a progressive and chronic bone disorder characterized by low bone mass and microarchitectural deterioration of skeletal tissues. Osteoporosis leads to alteration in bone mineral content resulting in decreased bone strength with elevated fracture risks frequently associated with greater morbidity. The latest research in the area of photomedicine had sparked interest in harnessing the active components from plants in both disease control and management across the globe. We in the present review have taken a comprehensive approach to identify forty known plants and their phytoconstituents, which encompasses (i) the genetic diversity of various plants, (ii) their active components and (iii) their osteoprotective role in osteoporosis. Thus, the present review is an attempt for the first time to collectively document the therapeutic properties of valuable medicinal plants in preventing and treating bone loss in osteoporosis.
骨质疏松症是一种以骨量低、骨骼组织微结构恶化为特征的进行性和慢性骨骼疾病。骨质疏松症导致骨矿物质含量的改变，从而导致骨强度降低，骨折风险增加，常伴有更高的发病率。光医学领域的最新研究引起了人们的兴趣，希望利用植物中的活性成分来控制和管理全球的疾病。在本综述中，我们采用了一种全面的方法来确定四十种已知的植物及其植物成分，其中包括(i) 各种植物的遗传多样性，(ii) 它们的活性成分，以及 (iii) 它们在骨质疏松症中的骨保护作用。因此，本综述首次试图集体记录有价值的药用植物在预防和治疗骨质疏松症中的骨丢失方面的治疗特性。
