Department of Cardiology, Second Affiliated Hospital of Soochow University, Suzhou, China.
Department of Cardiology, Second Affiliated Hospital of Soochow University, Suzhou, China
Postgrad Med J. 2021 Mar;97(1145):164-167. doi: 10.1136/postgradmedj-2019-137434. Epub 2020 Feb 29.
Heart failure with preserved ejection fraction (HFpEF) has received widespread attention in recent years. There is currently a lack of valuable predictors for the prognosis of this disease. Here, we aimed to identify a non-invasive scoring system that can effectively predict 1-year rehospitalisation for patients with HFpEF.
We included 151 consecutive patients with HFpEF in a prospective cohort study and investigated the association between HFPEF score and 1-year readmission for heart failure using multivariate Cox regression analysis.
Our findings indicated that obesity, age >70 years, treatment with ≥2 antihypertensives, echocardiographic E/e' ratio >9 and pulmonary artery pressure >35 mm Hg were independent predictors of 1-year readmission. Three models (support vector machine, decision tree in R and Cox regression analysis) proved that HFPEF score could effectively predict 1-year readmission for patients with HFpEF (area under the curve, 0.910, 0.899 and 0.771, respectively; p<0.001).
Our study demonstrates that the HFPEF score has excellent predictive value for 1-year rehospitalisation of patients with HFpEF.
近年来，射血分数保留的心力衰竭（HFpEF）受到了广泛关注。目前，对于这种疾病的预后还缺乏有价值的预测指标。在这里，我们旨在确定一种非侵入性评分系统，该系统可以有效地预测 HFpEF 患者的 1 年再入院情况。
我们进行了一项前瞻性队列研究，纳入了 151 例连续的 HFpEF 患者，并使用多变量 Cox 回归分析研究了 HFPEF 评分与 1 年心力衰竭再入院之间的关系。
我们的研究结果表明，肥胖、年龄>70 岁、使用≥2 种降压药、超声心动图 E/e' 比值>9 和肺动脉压>35mmHg 是 1 年再入院的独立预测因素。支持向量机、R 语言决策树和 Cox 回归分析这 3 种模型均证明 HFPEF 评分可以有效地预测 HFpEF 患者的 1 年再入院情况（曲线下面积分别为 0.910、0.899 和 0.771，p<0.001）。
我们的研究表明，HFPEF 评分对 HFpEF 患者 1 年再入院具有很好的预测价值。
