HFPEF 评分可预测射血分数保留的心力衰竭患者 1 年内再住院的情况。
HFPEF score predicts 1-year rehospitalisation of patients with heart failure with preserved ejection fraction.
机构信息
Department of Cardiology, Second Affiliated Hospital of Soochow University, Suzhou, China.
Department of Cardiology, Second Affiliated Hospital of Soochow University, Suzhou, China
出版信息
Postgrad Med J. 2021 Mar;97(1145):164-167. doi: 10.1136/postgradmedj-2019-137434. Epub 2020 Feb 29.
BACKGROUND
Heart failure with preserved ejection fraction (HFpEF) has received widespread attention in recent years. There is currently a lack of valuable predictors for the prognosis of this disease. Here, we aimed to identify a non-invasive scoring system that can effectively predict 1-year rehospitalisation for patients with HFpEF.
METHODS
We included 151 consecutive patients with HFpEF in a prospective cohort study and investigated the association between HFPEF score and 1-year readmission for heart failure using multivariate Cox regression analysis.
RESULTS
Our findings indicated that obesity, age >70 years, treatment with ≥2 antihypertensives, echocardiographic E/e' ratio >9 and pulmonary artery pressure >35 mm Hg were independent predictors of 1-year readmission. Three models (support vector machine, decision tree in R and Cox regression analysis) proved that HFPEF score could effectively predict 1-year readmission for patients with HFpEF (area under the curve, 0.910, 0.899 and 0.771, respectively; p<0.001).
CONCLUSION
Our study demonstrates that the HFPEF score has excellent predictive value for 1-year rehospitalisation of patients with HFpEF.
背景
近年来，射血分数保留的心力衰竭（HFpEF）受到了广泛关注。目前，对于这种疾病的预后还缺乏有价值的预测指标。在这里，我们旨在确定一种非侵入性评分系统，该系统可以有效地预测 HFpEF 患者的 1 年再入院情况。
方法
我们进行了一项前瞻性队列研究，纳入了 151 例连续的 HFpEF 患者，并使用多变量 Cox 回归分析研究了 HFPEF 评分与 1 年心力衰竭再入院之间的关系。
结果
我们的研究结果表明，肥胖、年龄>70 岁、使用≥2 种降压药、超声心动图 E/e' 比值>9 和肺动脉压>35mmHg 是 1 年再入院的独立预测因素。支持向量机、R 语言决策树和 Cox 回归分析这 3 种模型均证明 HFPEF 评分可以有效地预测 HFpEF 患者的 1 年再入院情况（曲线下面积分别为 0.910、0.899 和 0.771，p<0.001）。
结论
我们的研究表明，HFPEF 评分对 HFpEF 患者 1 年再入院具有很好的预测价值。
Zotero 插件