Department of Neurology, College of Medicine Imam Abdulrahman Bin Faisal University, King Fahad University Hospital, Al Ahsa, Kingdom of Saudi Arabia. E-mail.
Saudi Med J. 2020 Mar;41(3):290-295. doi: 10.15537/smj.2020.3.24910.
To determine relationship between fatigue, depression with the registration in multiple sclerosis (MS) society activity, and stress with the risk developing a new attack in patients with Relapsing remitting MS (RRMS) in the Kingdom of Saudi Arabia (KSA).
This was a cohort retrospective study conducted in the KSA between July 2018 and July 2019 which included a total of 465 RRMS patients. Data were collected during interviews using the Beck Depression Inventory (BDI) and Modified Fatigue Impacts Scale (MFIS). Demographic and clinical data were also collected.
Of 465 participants, 317 expressed psychological stress before the last attack, 67 of whom developed an attack within 4 weeks, and 250 of whom developed an attack after 4 weeks. Significantly lower BDI scores were associated with registration in MS associations (p=0.003, df = 5). Significantly lower MFIS scores were associated with registration in MS associations (p=0.001, df = 5).
The majority of RRMS patients have a significant fatigue and depression, and there are significant relationships between registration in the MS society and MFIS and BDI scores where patients who officially registered in MS society have lower score in MFIS and BDI. we recommend regular follow-ups with a psychologist and/or registration with MS societies.
在沙特阿拉伯王国（KSA）的复发性缓解型多发性硬化症（RRMS）患者中，确定疲劳、抑郁与多发性硬化症协会注册活动的关系，以及压力与发生新发作的风险之间的关系。
这是一项在 2018 年 7 月至 2019 年 7 月期间在 KSA 进行的队列回顾性研究，共纳入了 465 名 RRMS 患者。数据是通过贝克抑郁量表（BDI）和改良疲劳影响量表（MFIS）访谈收集的。还收集了人口统计学和临床数据。
在 465 名参与者中，有 317 名在最近一次发作前表达了心理压力，其中 67 名在 4 周内发作，250 名在 4 周后发作。与 MS 协会注册相关的 BDI 评分显著降低（p=0.003，df=5）。与 MS 协会注册相关的 MFIS 评分显著降低（p=0.001，df=5）。
大多数 RRMS 患者都有明显的疲劳和抑郁，MS 协会的注册与 MFIS 和 BDI 评分之间存在显著关系，即正式注册于 MS 协会的患者 MFIS 和 BDI 评分较低。我们建议定期接受心理学家随访和/或在 MS 协会注册。
