Ryan Joseph J, Umfleet Laura Glass, Gontkovsky Samuel T
a Department of Psychological Science , University of Central Missouri , Warrensburg , MO , USA.
b Division of Neuropsychology , Medical College of Wisconsin , Milwaukee , WI , USA.
Int J Neurosci. 2016 Nov;126(11):1025-9. doi: 10.3109/00207454.2015.1101596. Epub 2015 Oct 23.
We evaluated the utility of prorating appropriate combinations of two, six and eight Wechsler Adult Intelligence Scale - Fourth Edition (WAIS - IV) subtests for estimating the Verbal Comprehension Index (VCI), Perceptual Reasoning Index (PRI), Full Scale IQ (FSIQ) and General Ability Index (GAI) in a sample of individuals diagnosed with multiple sclerosis (MS). Forty-eight outpatients completed the WAIS - IV and Wechsler Memory Scale - Fourth Edition (WMS - IV) as part of a comprehensive neuropsychological battery. Means for age, education and duration of diagnosis were 42.35, 14.21 and 8.30 years, respectively. Paired t-tests showed no significant differences between prorated and standard means for VCI (93.46 vs. 93.73), PRI (90.19 vs. 89.44), FSIQ (88.53 vs. 88.47) or GAI (90.56 vs. 90.65). Correlations between prorated and standard composites were ≥0.89 in every instance. Correlations between the standard and prorated composites and education, disability status and WMS - IV indexes did not reveal a single contrast, where the correlations were significantly different. The present findings support the use of the two-subtest VCI and PRI composites and the eight-subtest FSIQ and four-subtest GAI in the assessment of patients with MS.
我们评估了在诊断为多发性硬化症（MS）的个体样本中，按比例分配韦氏成人智力量表第四版（WAIS-IV）的两个、六个和八个子测验的适当组合，用于估计言语理解指数（VCI）、知觉推理指数（PRI）、全量表智商（FSIQ）和一般能力指数（GAI）的效用。48名门诊患者完成了WAIS-IV和韦氏记忆量表第四版（WMS-IV），作为综合神经心理测验的一部分。年龄、受教育程度和诊断时长的均值分别为42.35岁、14.21年和8.30年。配对t检验显示，VCI（93.46对93.73）、PRI（90.19对89.44）、FSIQ（88.53对88.47）或GAI（90.56对90.65）的按比例分配均值与标准均值之间无显著差异。在每种情况下，按比例分配的和标准的合成指数之间的相关性均≥0.89。标准合成指数与按比例分配的合成指数与受教育程度、残疾状况和WMS-IV指数之间的相关性未显示出单一的对比，即相关性存在显著差异。本研究结果支持在MS患者评估中使用两个子测验的VCI和PRI合成指数、八个子测验的FSIQ和四个子测验的GAI。
