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单髁膝关节骨关节炎行部分膝关节置换术和高位胫骨截骨术后的翻修风险及不良结局:一项全国性队列研究。

Risk of Revision and Adverse Outcomes Following Partial Knee Replacement and High Tibial Osteotomy for Unicompartmental Knee Osteoarthritis: A Nationwide Cohort Study.

作者信息

Lee Sun-Ho, Kim Hae-Rim, Song Eun-Kyoo, Seon Jong-Keun

机构信息

Department of Orthopedic Surgery, Chonnam National University Medical School and Hospital, 322 Seoyang-ro, Hwasun-eup, Hwasun-gun, Jeollanam-do Republic of Korea.

College of Natural Science, School of Statistics, University of Seoul, Seoul, Republic of Korea.

出版信息

Indian J Orthop. 2021 Sep 21;55(5):1101-1110. doi: 10.1007/s43465-021-00517-z. eCollection 2021 Oct.

Abstract

PURPOSE

To investigate comparative study for potential associations of adverse outcomes as well as survival rates after high tibial osteotomy (HTO) and unicompartmental knee arthroplasty (UKA).

METHODS

We reviewed the Korean National Health Insurance claims database from January 1, 2007 to May 31, 2019. A total of 90,705 patients aged 30-90 years who were newly treated for HTO or UKA were identified considering their eligibility. We performed four rounds of propensity score matching to reduce imbalance of baseline characteristics, especially disparities among different age groups. Multivariable logistic regression models were used to compare the risk of revision and various unwanted medical problems between HTO and UKA treatment groups after propensity score matching.

RESULTS

23,563 matched patients were assigned to each group on the basis of propensity score. HTO showed higher risk of revision than UKA at 5 years, 10 years and the whole observed period (hazard ratio: 1.21, 95% CI 1.10-1.34). Deep vein thromboembolism (0.27, 0.21-0.35), and surgical site infection (0.37, 0.30-0.44) were less likely for HTOs than UKAs. Postoperative admission to intensive care unit was significantly lower with HTO (odds ratio: 0.40, 0.29-0.54) while rehospitalization within 30 days (1.27, 1.16-1.38) and 90 days (1.24, 1.18-1.30) were higher than UKA.

CONCLUSION

When choosing the surgical method for unicompartmental knee OA, not only the survival rate, but also the risk of other adverse outcomes should be considered. In particular, attention should be paid to the risk of developing deep vein thromboembolism and surgical site infection.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s43465-021-00517-z.

摘要

目的

探讨胫骨高位截骨术(HTO)和单髁膝关节置换术(UKA)后不良结局及生存率潜在关联的比较研究。

方法

我们回顾了2007年1月1日至2019年5月31日的韩国国民健康保险理赔数据库。考虑其 eligibility,共识别出90705例年龄在30 - 90岁之间新接受HTO或UKA治疗的患者。我们进行了四轮倾向评分匹配,以减少基线特征的不平衡,特别是不同年龄组之间的差异。倾向评分匹配后,使用多变量逻辑回归模型比较HTO和UKA治疗组之间翻修风险及各种不良医疗问题。

结果

根据倾向评分,每组分配了23563例匹配患者。在5年、10年及整个观察期内,HTO的翻修风险高于UKA(风险比:1.21,95%可信区间1.10 - 1.34)。HTO发生深静脉血栓栓塞(0.27,0.21 - 0.35)和手术部位感染(0.37,0.30 - 0.44)的可能性低于UKA。HTO术后入住重症监护病房的比例显著较低(优势比:0.40,0.29 - 0.54),而30天内(1.27,1.16 - 1.38)和90天内(1.24,1.18 - 1.30)的再次住院率高于UKA。

结论

在选择单髁膝关节骨关节炎的手术方法时,不仅应考虑生存率,还应考虑其他不良结局的风险。特别是,应注意发生深静脉血栓栓塞和手术部位感染的风险。

补充信息

在线版本包含可在10.1007/s43465 - 021 - 00517 - z获取的补充材料。

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