Patel Tulsi, Sosa-Stanley Jessica N, Evans-Hoeker Emily, Osborne Janet L
Department of Obstetrics and Gynecology, Virginia Tech Carilion Clinic, United States.
Department of Obstetrics and Gynecology, Division of Minimally Invasive Gynecologic Surgery, St. Luke's University Hospital and Health Network, United States.
Gynecol Oncol Rep. 2020 Jan 30;32:100541. doi: 10.1016/j.gore.2020.100541. eCollection 2020 May.
Development of endometrial stromal sarcoma during in vitro fertilization (IVF) is rare. We encountered a case of endometrial stromal sarcoma (ESS) presenting as a new endometrial mass in a patient undergoing donor egg IVF, despite normal imaging and exams prior to and throughout treatment. To our knowledge, this is the only report describing the rapid growth of ESS during IVF treatment. When diagnosing an endometrial stromal sarcoma, it is important for the clinician and patient to be aware that full histologic inspection is required to distinguish it from a benign neoplasm. Given the need for a hysterectomy for definitive diagnosis, this case presents ethical challenges and potential for patient distress.
体外受精（IVF）期间发生子宫内膜间质肉瘤的情况罕见。我们遇到一例子宫内膜间质肉瘤（ESS），该病例发生在一名接受供卵IVF的患者身上，表现为新出现的子宫内膜肿物，尽管在治疗前及整个治疗过程中的影像学检查和各项检查均正常。据我们所知，这是唯一一篇描述IVF治疗期间ESS快速生长的报告。在诊断子宫内膜间质肉瘤时，临床医生和患者必须意识到需要进行全面的组织学检查以将其与良性肿瘤区分开来。鉴于明确诊断需要进行子宫切除术，该病例带来了伦理挑战以及患者痛苦的可能性。
