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在常规国民保健制度实践中,使用低剂量计算机断层扫描对高危人群进行肺癌靶向筛查的实施。

Implementation of targeted screening for lung cancer in a high-risk population within routine NHS practice using low-dose computed tomography.

机构信息

Research and Development, South Tyneside and Sunderland NHS Foundation Trust, South Shields, UK

Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.

出版信息

Thorax. 2020 Apr;75(4):348-350. doi: 10.1136/thoraxjnl-2019-214303. Epub 2020 Mar 3.

Abstract

We report a primary care-based lung cancer targeted screening programme using low-dose CT (LDCT) in South Tyneside and Sunderland. Ever smokers with ≥10 pack-years aged 55-74 years were identified at annual COPD review. 925 individuals attended for LDCT. 2% (n=19/925) had lung cancer diagnosed. 66.7% (n=14/21) had early stage disease and 78.9% (n=15/19) were offered treatment with curative intent. 79.3% of individuals attending for LDCT were ranked in the lowest deprivation quintiles. This approach has been successfully established in routine NHS practice; it is effective with improvements in stage of disease and engages individuals in deprived areas.

摘要

我们报告了一个基于初级保健的肺癌靶向筛查计划,该计划在南泰恩赛德和桑德兰使用低剂量 CT(LDCT)。在每年的 COPD 审查中,确定≥10 包年的吸烟史且年龄在 55-74 岁的人群进行 LDCT 检查。925 人参加了 LDCT 检查。2%(n=19/925)被诊断为肺癌。66.7%(n=14/21)为早期疾病,78.9%(n=15/19)接受了治愈性治疗。参加 LDCT 检查的 79.3%的人被归入最低贫困五分位数。这种方法已成功地在常规国民保健制度实践中建立;它具有有效性,可改善疾病分期,并使贫困地区的个人参与其中。

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