Faculty of Medicine, Tanta University, Tanta, Egypt.
Aesthetic Plast Surg. 2020 Dec;44(6):2259-2267. doi: 10.1007/s00266-020-01661-x. Epub 2020 Mar 3.
Freckles are typical epidermal pigmented disorders that occur at sun-exposed areas, presenting with dark-brown or light-brown circular hyperpigmentation. A lot of treatment modalities have been used for treatment of freckles like chemicals, electrosurgery and cryotherapy. These treatments may cause undesirable side effects such as scaring (Sarkar et al. in Indian J Dermatol 62(6):578-584, 2017). Microdermabrasion has been used in treatment of freckles; however, the results are not satisfactory, as it removes the outermost layer of the epidermis only (El-Domyati et al. in J Cosmet Dermatol 15(4):503-513, 2016). Also ablative lasers and non-ablative lasers have been used but have not proved to be completely satisfactory and share a common risk of post-inflammatory hyperpigmentation (Jang et al. in Dermatol Surg 26:231-234, 2000). In our study, we have used epiderm-abrasion-assisted intensive pulsed light (IPL) and radiofrequency (RF) to study their effect in treatment of freckles.
this prospective controlled clinical trial was carried out on 48 patients, who presented with extensive facial freckles, in the period between March 2015 and April 2018. The epiderm-abrasion procedure was performed first, and then, electro-photobiomodulation sessions were started two weeks later.
This study was carried out on 48 patients, 39 female and 9 males. Their age ranged between 12 and 58 years old. According to Fitzpatrick classification, four patients were type II, 30 patients were type III, and 14 patients were type IV. The results were excellent in 32 cases, good in 12 cases, fair in four cases, and we have no poor results. Side effects like hyperpigmentation were reported in three patients (6.3%), one case grade III and two cases grade IV Fitzpatrick skin type. No cases with hypopigmentation, or scars, were reported.
Epiderm-abrasion and electro-photobiomodulation (IPL&RF) are effective methods in treatment of facial freckles. Some complications may occur post-procedure such as hyperpigmentation, hypopigmentation and abnormal scarring.
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雀斑是一种典型的表皮色素沉着性疾病，常发生于暴露于阳光的部位，表现为深棕色或浅棕色的圆形色素沉着。有许多治疗方法已被用于治疗雀斑，如化学疗法、电外科和冷冻疗法。这些治疗方法可能会导致不理想的副作用，如疤痕（Sarkar 等人，印度皮肤病学杂志 62（6）：578-584，2017）。微晶磨皮术已被用于治疗雀斑；然而，结果并不令人满意，因为它只去除表皮的最外层（El-Domyati 等人，美容皮肤病学杂志 15（4）：503-513，2016）。还有剥脱性激光和非剥脱性激光已被使用，但尚未被证明完全令人满意，并且都有炎症后色素沉着过度的共同风险（Jang 等人，皮肤病外科学 26：231-234，2000）。在我们的研究中，我们使用表皮磨蚀辅助强脉冲光（IPL）和射频（RF）来研究它们在治疗雀斑中的效果。
这项前瞻性对照临床试验于 2015 年 3 月至 2018 年 4 月期间对 48 名面部有广泛雀斑的患者进行了研究。首先进行表皮磨蚀术，然后在两周后开始进行光电生物调节治疗。
这项研究共纳入 48 名患者，其中 39 名为女性，9 名为男性。他们的年龄在 12 至 58 岁之间。根据 Fitzpatrick 分类，4 名患者为 II 型，30 名患者为 III 型，14 名患者为 IV 型。结果为 32 例优秀，12 例良好，4 例一般，我们没有差的结果。有 3 名患者（6.3%）报告出现了色素沉着过度等副作用，其中 1 例为 III 级，2 例为 IV 级 Fitzpatrick 皮肤类型。没有出现色素减退或疤痕的病例。
表皮磨蚀术和光电生物调节（IPL&RF）是治疗面部雀斑的有效方法。术后可能会出现一些并发症，如色素沉着过度、色素减退和异常疤痕形成。
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