Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 106 91 Stockholm, Sweden.
RG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Department of Medicine, Technische Universität München, Munich, Germany.
Cell Metab. 2020 Mar 3;31(3):443-444. doi: 10.1016/j.cmet.2020.02.007.
The gut microbiota plays an important role for the absorption of nutrients and the maintenance of metabolism, potentially impacting the development of human metabolic disorders such as obesity and type 2 diabetes. In this issue of Cell Metabolism, Krisko et al. (2020) demonstrate that the gut microbiota regulates glucose homeostasis solely via hepatic gluconeogenesis and not via thermogenic adipose tissue as suggested previously.
肠道微生物群在营养吸收和新陈代谢维持方面发挥着重要作用，可能会影响人类代谢紊乱的发展，如肥胖和 2 型糖尿病。在本期《细胞代谢》中，Krisko 等人（2020 年）表明，肠道微生物群仅通过肝脏糖异生而不是先前提出的产热脂肪组织来调节葡萄糖稳态。
