Lavdaniti Maria, Tilaveridis Ioannis, Palitzika Dimitra, Kyrgidis Athanasios, Triaridis Stefanos, Vachtsevanos Konstantinos, Kosintzi Angeliki, Antoniades Konstantinos
Nursing Department, International Hellenic University, 57400 Thessaloniki, Greece.
Oral and Maxillofacial Surgery, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
J Clin Med. 2022 Dec 6;11(23):7235. doi: 10.3390/jcm11237235.
Cancer of the oral cavity is one of the most common cancers all over the world. Oral cancer and its treatment impacts on patients' Quality of Life (QOL). The purpose of the present study was to assess oral cancer patients' QOL after the completion of surgical therapy, and to investigate factors affecting it. This was a prospective cohort study, conducted at the Department of Oral & Maxillofacial Surgery, of a large general public hospital in Northern Greece. The sample consisted of 135 consecutive eligible cancer patients. Three distinct questionnaires were used. The first one included questions regarding the participants' demographic characteristics and relevant clinical information. The second comprised the European Organization for Research and Treatment core module (EORTC QLQ-C30) and its head and neck module EORTC QLQ-H&N35. The third was the Functional Assessment of Cancer Therapy-General (FACT-G) assessment of quality of life. We also included the physician-completed Karnofsky scale to assess the functional status of the participants. We found that location of the tumor affects QOL and specifically social contact (H = 17.89, = 0.001), on the first assessment, and nutritional supplements (H = 22.49, = 0.000), on the fourth assessment. QOL in patients deteriorates immediately after treatment but significantly improves over time. Health care professionals should take into account these results and arrange care plans in order to find ways to increase patients' QOL.
口腔癌是全球最常见的癌症之一。口腔癌及其治疗会影响患者的生活质量（QOL）。本研究的目的是评估手术治疗完成后口腔癌患者的生活质量，并调查影响生活质量的因素。这是一项前瞻性队列研究，在希腊北部一家大型综合公立医院的口腔颌面外科进行。样本包括135名连续入选的合格癌症患者。使用了三种不同的问卷。第一种包括有关参与者人口统计学特征和相关临床信息的问题。第二种包括欧洲癌症研究与治疗组织核心模块（EORTC QLQ-C30）及其头颈模块EORTC QLQ-H&N35。第三种是癌症治疗功能评估通用版（FACT-G）生活质量评估。我们还纳入了医生填写的卡氏量表来评估参与者的功能状态。我们发现，肿瘤位置在首次评估时会影响生活质量，尤其是社交接触（H = 17.89，P = 0.001），在第四次评估时会影响营养补充（H = 22.49，P = 0.000）。患者的生活质量在治疗后立即恶化，但随着时间的推移会显著改善。医疗保健专业人员应考虑这些结果并安排护理计划，以便找到提高患者生活质量的方法。
