Amini Shirin, Shirali Saeed, Jafarirad Sima, Ehsani Hajar, Mohseni Houra, Bargard Mehdi Sayah
Department of Nutrition, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Laboratory Sciences, Hyperlipidemia Research Center, Faculty of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Int J Prev Med. 2019 Oct 9;10:185. doi: 10.4103/ijpvm.IJPVM_372_17. eCollection 2019.
Depression and obesity are among the increasingly publicized health problems, both being related to critical complications, and increasing the risk of substantial morbidity and mortality. An increasing number of documents indicate that obesity affects mental status, low serum cholesterol levels, and is related to depressive symptoms. The purpose of the present study was to evaluate the possible significant difference in lipid profile levels, body mass index (BMI), waist circumference (WC), and blood pressure (BP), between depressive and nondepressive older adults.
This was a case-control study where 107 patients, over 65-year-old, were enrolled in this study. Serum total cholesterol, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol (LDL-C), triglycerides (TG), BP, and fasting blood sugar were measured. Data were analyzed using the statistical SPSS software version 22. Independent -test was used to compare the results between the two groups and the Chi-square test was used to compare categorical variables. In addition, nonparametric Mann-Whitney test was used to evaluate the data.
The depressive group showed significant lower BMI, WC, LDL-C, and TG ( < 0.001, < 0.001, < 0.016, and < 0.014). Furthermore, the findings showed significantly higher systolic and diastolic BP in participants who had shown depressive symptoms ( < 0.035 and < 0.024).
The findings suggest that a low BMI, serum LDL-C, and TG are related to depressive symptoms the Iranian elderly.
抑郁症和肥胖是日益受到广泛关注的健康问题，二者均与严重并发症相关，且会增加高发病率和死亡率的风险。越来越多的文献表明，肥胖会影响精神状态、降低血清胆固醇水平，并与抑郁症状有关。本研究的目的是评估抑郁和非抑郁的老年人在血脂水平、体重指数（BMI）、腰围（WC）和血压（BP）方面可能存在的显著差异。
这是一项病例对照研究，107名65岁以上的患者参与了本研究。测量了血清总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇（LDL-C）、甘油三酯（TG）、血压和空腹血糖。使用统计软件SPSS 22版对数据进行分析。独立样本t检验用于比较两组结果，卡方检验用于比较分类变量。此外，非参数曼-惠特尼检验用于评估数据。
抑郁组的BMI、WC、LDL-C和TG显著较低（P<0.001，P<0.001，P<0.016，P<0.014）。此外，研究结果显示，出现抑郁症状的参与者的收缩压和舒张压显著较高（P<0.035和P<0.024）。
研究结果表明，低BMI、血清LDL-C和TG与伊朗老年人的抑郁症状有关。
