Viale J P, Annat G, Bertrand O, Thouverez B, Hoen J P, Motin J
Department of Anaesthesia and Intensive Care, Hôpital Edouard Herriot, Lyon, France.
Acta Anaesthesiol Scand. 1988 Nov;32(8):691-7. doi: 10.1111/j.1399-6576.1988.tb02810.x.
We report a system for the continuous measurement of oxygen uptake (VO2) and carbon dioxide output (VCO2) during open-circuit anaesthesia. Gas concentrations were measured by a mass-spectrometer, and expired flow by a pneumotachograph. The values measured by the system were compared in vitro to values produced by a nitrogen-dilution technique. Excellent correlations were found. Continuous measurements were performed in 21 patients anaesthetized for abdominal surgery. Compared to pure intravenous anaesthesia (flunitrazepam-fentanyl), anaesthesia including the administration of nitrous oxide or nitrous oxide and halothane led to more pronounced and sustained decreases in VO2 and core temperature, with a better cardiovascular stability. Two hours postoperatively, VO2 was not different from preoperative values. After a transient increase at the onset of anaesthesia, the respiratory exchange ratio (VCO2/VO2) returned to preoperative values, and then remained subsequently unchanged. Based on these observations, the system described provides an accurate approach to noninvasively monitoring the pulmonary gas exchange in the operating room.
我们报告了一种用于在开放回路麻醉期间连续测量氧摄取量（VO₂）和二氧化碳排出量（VCO₂）的系统。气体浓度通过质谱仪测量，呼出气流通过呼吸速度描记器测量。该系统测量的值在体外与氮稀释技术产生的值进行了比较。发现相关性极佳。对21例接受腹部手术麻醉的患者进行了连续测量。与单纯静脉麻醉（氟硝西泮-芬太尼）相比，包括使用氧化亚氮或氧化亚氮和氟烷的麻醉导致VO₂和核心温度更明显且持续的下降，同时心血管稳定性更好。术后两小时，VO₂与术前值无差异。在麻醉开始时短暂升高后，呼吸交换率（VCO₂/VO₂）恢复到术前值，随后保持不变。基于这些观察结果，所描述的系统为在手术室中无创监测肺气体交换提供了一种准确的方法。
