Noe F E, Whitty A J, Davies K R, Wickham B L
Anesth Analg. 1980 Apr;59(4):263-9.
Expired gas flow volume (VE), carbon dioxide excretion (Vco2) and oxygen consumption (Vo2) were measured continuously for 2-minute periods at 15-minute intervals during at least 75 minutes of general anesthesia and surgery in clinical patients. Analog tape-recorded outputs from an infrared CO2 analyzer, from a rapid polarographic O2 analyzer, and from a pneumotachograph were subsequently processed by a general purpose digital computer. Values for VE, VCO2, and VO2 in a group of 50 normal paralyzed endotracheally intubated women with balanced N2O-O2-fentanyl anesthesia for lower abdominal surgery compare favorably with the few published reports of similar measurements. The measured response to anesthesia and surgery in most patients included a progressive increase in O2 uptake and a concurrent but not necessarily simultaneous decrease in CO2 output with a consequent decreased respiratory gas exchange ratio (RE).
在临床患者的全身麻醉和手术过程中，至少75分钟内，每隔15分钟连续测量2分钟的呼出气体流量（VE）、二氧化碳排出量（Vco2）和耗氧量（Vo2）。来自红外二氧化碳分析仪、快速极谱氧分析仪和呼吸流速计的模拟磁带记录输出随后由通用数字计算机进行处理。一组50名接受氧化亚氮-氧气-芬太尼平衡麻醉、气管内插管且瘫痪的正常女性患者进行下腹部手术时的VE、VCO2和VO2值，与少数几篇发表的类似测量报告相比，情况良好。大多数患者对麻醉和手术的测量反应包括氧摄取逐渐增加，同时二氧化碳排出量下降，但不一定同步，从而导致呼吸气体交换率（RE）降低。
