Department of Oral Pathology, Federal University of Rio Grande do Norte, Natal, Brazil.
Am J Clin Pathol. 2020 Jun 8;154(1):15-22. doi: 10.1093/ajcp/aqaa027.
The aim of this systematic review was to provide an overview of the oral and maxillofacial solitary fibrous tumor (SFT) in order to determine its clinicopathologic characteristics and biological behavior.
We conducted a systematic review in May 2019 in multiple databases. Cases diagnosed as SFT in the oral cavity and maxillofacial complex were included.
Seventy-three published articles were included in our systematic review, corresponding to a total of 154 cases. SFT showed a slight female predilection (53.2%), and the cheek mucosa/cheek, tongue, and palate were the most affected anatomical sites. The mean size of SFT in the oral cavity and maxillofacial region at diagnosis was 1.4 cm. Histologic features of malignancy by morphologic analysis (P < .001) were significantly associated with a larger tumor size. Surgical excision was the most frequent therapeutic modality. Recurrence and metastasis were uncommon findings in our sample.
Histologic features of malignancy can be important parameters of tumor behavior. Adequate surgical treatment and long-term follow-up are required for these cases.
本系统回顾的目的是概述口腔颌面部孤立性纤维肿瘤（SFT），以确定其临床病理特征和生物学行为。
我们于 2019 年 5 月在多个数据库中进行了系统回顾。纳入口腔颌面部复合体中诊断为 SFT 的病例。
本系统回顾共纳入 73 篇已发表的文章，共计 154 例。SFT 女性略多见（53.2%），颊黏膜/颊部、舌和 palate 是最常受累的解剖部位。口腔颌面部 SFT 诊断时的平均大小为 1.4cm。形态学分析的恶性组织学特征（P<.001）与较大的肿瘤大小显著相关。手术切除是最常见的治疗方式。在我们的样本中，复发和转移并不常见。
恶性组织学特征可能是肿瘤行为的重要参数。这些病例需要进行充分的手术治疗和长期随访。
