Department of Pediatrics, University of Pennsylvania, Vaxconsult, Doylestown, Pennsylvania, USA.
J Infect Dis. 2020 Mar 5;221(Suppl 1):S123-S127. doi: 10.1093/infdis/jiz448.
The way to a successful vaccine against human cytomegalovirus is hampered by the peculiar biology of this infection. However, some candidate vaccines have been shown to protect seronegative women and transplant recipients, and we should know soon whether they can prevent congenital infection.
针对人类巨细胞病毒的成功疫苗研制之路受到这种感染特殊生物学性质的阻碍。然而,一些候选疫苗已被证明可以保护血清阴性的妇女和移植受者,我们应该很快就会知道它们是否能预防先天性感染。