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Med Oral Patol Oral Cir Bucal. 2020 May 1;25(3):e318-e325. doi: 10.4317/medoral.23181.
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本文引用的文献

1
Periodontitis and diabetes.牙周炎与糖尿病。
Br Dent J. 2019 Oct;227(7):577-584. doi: 10.1038/s41415-019-0794-5.
2
Development and validation of a predictive model for periodontitis using NHANES 2011-2012 data.利用 NHANES 2011-2012 数据开发和验证牙周炎预测模型。
J Clin Periodontol. 2019 Apr;46(4):420-429. doi: 10.1111/jcpe.13098. Epub 2019 Mar 19.
3
Estimation of salivary and serum alkaline phosphatase level as a diagnostic marker in type-2 diabetes mellitus with periodontal health and disease: A clinico-biochemical study.评估唾液和血清碱性磷酸酶水平作为2型糖尿病伴牙周健康与疾病的诊断标志物:一项临床生化研究。
J Oral Maxillofac Pathol. 2018 Sep-Dec;22(3):445. doi: 10.4103/jomfp.JOMFP_212_18.
4
Evaluation of serum and salivary alkaline phosphatase levels in chronic periodontitis patients before and after nonsurgical periodontal therapy.慢性牙周炎患者非手术牙周治疗前后血清和唾液碱性磷酸酶水平的评估
J Indian Soc Periodontol. 2018 Nov-Dec;22(6):487-491. doi: 10.4103/jisp.jisp_133_18.
5
Effects of periodontal disease on systemic health.牙周病对全身健康的影响。
Dis Mon. 2019 Jun;65(6):185-192. doi: 10.1016/j.disamonth.2018.09.011. Epub 2018 Oct 29.
6
From blood coagulation to innate and adaptive immunity: the role of platelets in the physiology and pathology of autoimmune disorders.从血液凝固到先天和适应性免疫:血小板在自身免疫性疾病的生理和病理中的作用。
Rheumatol Int. 2018 Jun;38(6):959-974. doi: 10.1007/s00296-018-4001-9. Epub 2018 Feb 28.
7
Scientific evidence on the links between periodontal diseases and diabetes: Consensus report and guidelines of the joint workshop on periodontal diseases and diabetes by the International diabetes Federation and the European Federation of Periodontology.牙周病与糖尿病关联的科学证据:国际糖尿病联合会和欧洲牙周病学联合会联合牙周病与糖尿病研讨会的共识报告和指南。
Diabetes Res Clin Pract. 2018 Mar;137:231-241. doi: 10.1016/j.diabres.2017.12.001. Epub 2017 Dec 5.
8
Periodontitis and Alzheimer's Disease: A Possible Comorbidity between Oral Chronic Inflammatory Condition and Neuroinflammation.牙周炎与阿尔茨海默病:口腔慢性炎症与神经炎症之间可能存在的共病关系。
Front Aging Neurosci. 2017 Oct 10;9:327. doi: 10.3389/fnagi.2017.00327. eCollection 2017.
9
Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases.慢性牙周炎、炎性细胞因子及其与其他慢性疾病的相互关系。
Postgrad Med. 2018 Jan;130(1):98-104. doi: 10.1080/00325481.2018.1396876. Epub 2017 Nov 8.
10
Association between obesity and periodontal disease. A systematic review of epidemiological studies and controlled clinical trials.肥胖与牙周病之间的关联。流行病学研究与对照临床试验的系统评价。
Med Oral Patol Oral Cir Bucal. 2017 Nov 1;22(6):e708-e715. doi: 10.4317/medoral.21786.

239 例患者的牙槽骨丧失、血小板和糖化血红蛋白水平。一项临床研究。

Alveolar bone loss, platelet and glycosylated haemoglobin levels in 239 patients. A clinical study.

机构信息

Oral Medicine, Oral Surgery and Implantology Unit Faculty of Medicine and Dentistry Santiago de Compostela University Entrerríos s/n, Santiago de Compostela C.P. 15782, Spain

出版信息

Med Oral Patol Oral Cir Bucal. 2020 May 1;25(3):e318-e325. doi: 10.4317/medoral.23181.

DOI:10.4317/medoral.23181
PMID:32134896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7211374/
Abstract

BACKGROUND

The relation between periodontal disease and systemic pathologies is still not widespread among general practitioners. The aim of our study is to evaluate whether or not periodontal radiological diagnosis can aid the detection of blood alterations associated with acquired systemic diseases.

MATERIAL AND METHODS

This is a cross sectional study. All of the participants underwent a panoramic radiograph and a complete blood test. Morphological bone loss was considered as positive in those patients who showed radiographically more than 1 tooth with bone loss greater than or equal to the middle third of the root. The statistical analysis was performed by comparing the variables using the ANOVA or U-Mann-Whitney tests for independent samples with normal conditions. The correlation coefficient was analysed using the Pearson test.

RESULTS

239 patients were included in our study (96 men and 143 women) with an average age of 64.40 years. 59.04% of the patients were determined as morphological bone loss positive and had on average 4 teeth less than negative patients (p <0.0001). Also the average platelet levels in positive patients were lower (p = 0.024) and mean levels of HBA1c (p = 0.009) were higher.

CONCLUSIONS

Morphological bone loss parameter can be useful both for dentists and general practitioners to refer, subsequently, to periodontal specialist.

摘要

背景

牙周病与全身系统疾病之间的关系在全科医生中仍未得到广泛认识。我们的研究旨在评估牙周影像学诊断是否有助于发现与获得性全身疾病相关的血液变化。

材料和方法

这是一项横断面研究。所有参与者均接受了全景 X 光检查和全血细胞检查。在影像学上显示有 1 个以上牙齿的牙槽骨丧失大于或等于根的中三分之一的患者被认为存在形态性骨丧失阳性。使用方差分析或独立样本 U- Mann-Whitney 检验比较具有正态分布的变量。使用 Pearson 检验分析相关系数。

结果

本研究共纳入 239 例患者(96 名男性和 143 名女性),平均年龄为 64.40 岁。59.04%的患者被确定为形态性骨丧失阳性,平均比阴性患者少 4 颗牙齿(p <0.0001)。阳性患者的血小板平均水平也较低(p = 0.024),HBA1c 平均水平较高(p = 0.009)。

结论

形态性骨丧失参数对于牙医和全科医生都很有用,可以随后将患者转介给牙周病专科医生。