GRAS 规定——美国 FEMA GRAS 计划与风味物质的安全性和法规管理。
The GRAS provision - The FEMA GRAS program and the safety and regulation of flavors in the United States.
机构信息
The Flavor and Extract Manufacturers Association of the United States, 1101 17th Street, N.W., Suite 700, Washington, D.C, 20036, USA.
The Flavor and Extract Manufacturers Association of the United States, 1101 17th Street, N.W., Suite 700, Washington, D.C, 20036, USA.
出版信息
Food Chem Toxicol. 2020 Apr;138:111236. doi: 10.1016/j.fct.2020.111236. Epub 2020 Mar 2.
With the Food Additives Amendment of 1958 the U.S. Congress established the pre-market approval requirement for food additives unless such food ingredients were "generally recognized as safe" (GRAS). Beginning in 2010 with the publication of an audit by the U.S. Government Accountability Office, the GRAS provision has received much attention from regulators and policy-makers, the media, and non-governmental organizations. This report provides an overview and update of the policies, procedures, and scope of the GRAS program for flavor ingredients sponsored by the Flavor and Extract Manufacturers Association of the United States (FEMA), and its alignment with the requirements for GRAS conclusions established by Congress and FDA.
1958 年《食品添加剂修正案》（Food Additives Amendment）生效后，除非食品成分被认定为“普遍认为安全”（Generally Recognized as Safe，GRAS），否则美国国会对食品添加剂实施了上市前批准要求。自 2010 年美国政府问责局（U.S. Government Accountability Office）发布审计报告以来，GRAS 规定一直受到监管机构和政策制定者、媒体和非政府组织的关注。本报告概述并更新了美国香精和提取物制造商协会（Flavor and Extract Manufacturers Association of the United States，FEMA）赞助的风味成分 GRAS 计划的政策、程序和范围，以及其与国会和 FDA 为 GRAS 结论设定的要求的一致性。
Zotero 插件