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氧氟沙星治疗衣原体尿道炎

[Ofloxacin for the treatment of chlamydial urethritis].

作者信息

Yuri K, Terasaki T, Kitamori T, Azuma Y, Watanabe H, Araki H

机构信息

Department of Urology, Kyoto Prefectural University of Medicine.

出版信息

Hinyokika Kiyo. 1988 Sep;34(9):1687-90.

PMID:3213803
Abstract

The effect of Ofloxacin administered orally 600 mg everyday for 14 days was evaluated in 20 male patients with Chlamydial urethritis, in whom Chlamydia was identified from urethral secretion by immunohistochemical technique using monoclonal primary antibody specific for all known serotypes of Chlamydia trachomatis and psittaci. 19 out of the 20 patients showed an improvement of subjective and/or objective symptoms after the treatment. The Chlamydia reaction turned to negative in 13 patients and to (+/-) in another patient. The overall clinical effect was excellent in 7, good in 6 and poor in 7, showing a effective rate of 65%. No side effects were observed.

摘要

对20例衣原体尿道炎男性患者进行了评估,这些患者每天口服600毫克氧氟沙星,持续14天。通过使用针对沙眼衣原体和鹦鹉热衣原体所有已知血清型的单克隆一抗的免疫组化技术,从尿道分泌物中鉴定出衣原体。20例患者中有19例在治疗后主观和/或客观症状有所改善。13例患者的衣原体反应转为阴性,另1例转为(±)。总体临床效果为优7例,良6例,差7例,有效率为65%。未观察到副作用。

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