Origins of peanut allergy-causing antibodies.
作者信息
Wesemann Duane R, Nagler Cathryn R
机构信息
Department of Medicine, Division of Allergy and Clinical Immunology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Department of Pathology, Biological Sciences Division, The University of Chicago, Chicago, IL, USA.
出版信息
Science. 2020 Mar 6;367(6482):1072-1073. doi: 10.1126/science.aba8974.
Abstract
摘要
相似文献
1
Origins of peanut allergy-causing antibodies.引发花生过敏的抗体的起源。
Science. 2020 Mar 6;367(6482):1072-1073. doi: 10.1126/science.aba8974.
2
The predictive relationship between peanut- and Ara h 2-specific serum IgE concentrations and peanut allergy.花生特异性和Ara h 2特异性血清IgE浓度与花生过敏之间的预测关系。
J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):131-2.e1. doi: 10.1016/j.jaip.2014.10.014. Epub 2014 Dec 2.
3
Utility of Ara h 2 sIgE levels to predict peanut allergy in Canadian children.Ara h 2特异性IgE水平对预测加拿大儿童花生过敏的效用。
J Allergy Clin Immunol Pract. 2015 Nov-Dec;3(6):968-9. doi: 10.1016/j.jaip.2015.04.001. Epub 2015 May 1.
4
Epicutaneous immunotherapy for peanut allergy modifies IgG responses to major peanut allergens.花生过敏的经皮免疫疗法可改变对主要花生过敏原的IgG反应。
J Allergy Clin Immunol. 2019 Mar;143(3):1218-1221.e4. doi: 10.1016/j.jaci.2018.10.025. Epub 2018 Oct 31.
5
Linear epitope mapping of peanut allergens demonstrates individualized and persistent antibody-binding patterns.花生过敏原的线性表位图谱显示出个性化且持久的抗体结合模式。
J Allergy Clin Immunol. 2016 Dec;138(6):1728-1730. doi: 10.1016/j.jaci.2016.06.019. Epub 2016 Jul 15.
6
Loss of allergenic proteins during boiling explains tolerance to boiled peanut in peanut allergy.煮沸过程中变应原蛋白的丧失解释了花生过敏患者对水煮花生的耐受性。
J Allergy Clin Immunol. 2014 Sep;134(3):751-3. doi: 10.1016/j.jaci.2014.06.016. Epub 2014 Jul 25.
7
Peanut allergens.花生过敏原。
Mol Immunol. 2018 Aug;100:58-70. doi: 10.1016/j.molimm.2018.04.005. Epub 2018 Apr 19.
8
Type B CpG oligodeoxynucleotides induce Th1 responses to peanut antigens: modulation of sensitization and utility in a truncated immunotherapy regimen in mice.B 型 CpG 寡脱氧核苷酸诱导花生抗原的 Th1 反应：在小鼠中对致敏的调节作用和在缩短免疫治疗方案中的应用。
Mol Nutr Food Res. 2013 May;57(5):906-15. doi: 10.1002/mnfr.201200410. Epub 2013 Feb 5.
9
High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy.高分辨率表位作图通过 AllerScan 揭示了花生口服免疫治疗期间 IgE 和 IgG 库之间的关系。
Cell Rep Med. 2021 Oct 19;2(10):100410. doi: 10.1016/j.xcrm.2021.100410.
10
Peanut allergy: an evolving clinical challenge.花生过敏：一个不断演变的临床挑战。
Discov Med. 2011 Oct;12(65):319-28.
引用本文的文献
1
Whence and wherefore IgE?IgE 从何而来，又为何存在？
Immunol Rev. 2024 Sep;326(1):48-65. doi: 10.1111/imr.13373. Epub 2024 Jul 23.
2
A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice.一种厌氧棒状菌和乳果糖的合生制剂可预防和治疗小鼠食物过敏。
Cell Host Microbe. 2024 Jul 10;32(7):1163-1176.e6. doi: 10.1016/j.chom.2024.05.019. Epub 2024 Jun 20.
3
Origins and diversity of pan-isotype human bone marrow plasma cells.全同种型人类骨髓浆细胞的起源与多样性
bioRxiv. 2024 May 10:2024.05.08.592267. doi: 10.1101/2024.05.08.592267.
4
B cells and the microbiota: a missing connection in food allergy.B 细胞与微生物群：食物过敏中的缺失环节。
Mucosal Immunol. 2021 Jan;14(1):4-13. doi: 10.1038/s41385-020-00350-x. Epub 2020 Oct 26.
5
IgE producers in the gut expand the gut's role in food allergy.肠道中的IgE产生细胞扩大了肠道在食物过敏中的作用。
Nat Rev Gastroenterol Hepatol. 2020 Jul;17(7):384-386. doi: 10.1038/s41575-020-0309-5.
本文引用的文献
1
Chronic allergen exposure drives accumulation of long-lived IgE plasma cells in the bone marrow, giving rise to serological memory.慢性过敏原暴露会导致骨髓中长期存在的 IgE 浆细胞积累，从而产生血清学记忆。
Sci Immunol. 2020 Jan 10;5(43). doi: 10.1126/sciimmunol.aav8402.
2
The Microbiome and Food Allergy.肠道微生物群与食物过敏
Annu Rev Immunol. 2019 Apr 26;37:377-403. doi: 10.1146/annurev-immunol-042718-041621.
3
High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes.从单个 IgE B 细胞转录组中克隆的高亲和力过敏原特异性人抗体。
Science. 2018 Dec 14;362(6420):1306-1309. doi: 10.1126/science.aau2599.
4
Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.用结合过敏原并防止 IgE 结合的单克隆 IgG 抗体治疗猫过敏。
Nat Commun. 2018 Apr 12;9(1):1421. doi: 10.1038/s41467-018-03636-8.
5
Allergen-specific IgG antibody signaling through FcγRIIb promotes food tolerance.过敏原特异性 IgG 抗体通过 FcγRIIb 信号转导促进食物耐受。
J Allergy Clin Immunol. 2018 Jan;141(1):189-201.e3. doi: 10.1016/j.jaci.2017.03.045. Epub 2017 May 4.
6
Germinal Center B Cell Dynamics.生发中心B细胞动力学
Immunity. 2016 Sep 20;45(3):471-482. doi: 10.1016/j.immuni.2016.09.001.
7
Role of immunoglobulin G antibodies in diagnosis of food allergy.免疫球蛋白G抗体在食物过敏诊断中的作用。
Postepy Dermatol Alergol. 2016 Aug;33(4):253-6. doi: 10.5114/ada.2016.61600. Epub 2016 Aug 16.
8
The Microbiome, Timing, and Barrier Function in the Context of Allergic Disease.过敏性疾病背景下的微生物组、时间因素与屏障功能
Immunity. 2016 Apr 19;44(4):728-38. doi: 10.1016/j.immuni.2016.02.002.
9
Molecular Mechanisms of IgE Class Switch Recombination.IgE类别转换重组的分子机制
Curr Top Microbiol Immunol. 2015;388:21-37. doi: 10.1007/978-3-319-13725-4_2.
10
Oral immunotherapy induces IgG antibodies that act through FcγRIIb to suppress IgE-mediated hypersensitivity.口服免疫疗法可诱导产生通过FcγRIIb起作用的IgG抗体，以抑制IgE介导的超敏反应。
J Allergy Clin Immunol. 2014 Dec;134(6):1310-1317.e6. doi: 10.1016/j.jaci.2014.05.042. Epub 2014 Jul 16.
Zotero 插件