HIV 抗逆转录病毒药物的娱乐性使用及其对 HIV 暴露前预防和治疗的影响。
Recreational Use of HIV Antiretroviral Medication and Implications for HIV Pre-exposure Prophylaxis and Treatment.
机构信息
Department of Behavioral and Social Sciences and Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, 02912, USA.
Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
出版信息
AIDS Behav. 2020 Sep;24(9):2650-2655. doi: 10.1007/s10461-020-02821-5.
Abstract
Diversion of antiretroviral therapy (ART) for recreational use is concerning for countries with high HIV prevalence. This paper presents reports of recreational use of ART among adolescents from two HIV prevention studies in South Africa: (1) a cross-sectional survey of N = 200 adolescents and (2) a qualitative study of pre-exposure prophylaxis with N = 57 adolescents and N = 25 clinicians. Among adolescents, 3% used and 14% knew someone who used non-prescribed ART for recreational purposes. Administration included smoking (71%), snorting (15%), injecting (15%), ingesting (15%), and inserting (3%). Participants predicted increased crime as recreational use of ART increased. Future studies should investigate prevalence, composition, and diversion of ART from HIV prevention and treatment.
摘要
抗逆转录病毒疗法（ART）被滥用于娱乐用途，这引起了 HIV 高发国家的关注。本文报告了南非两项 HIV 预防研究中青少年群体 ART 被滥用于娱乐用途的情况：（1）对 200 名青少年进行的横断面调查，以及（2）对接受暴露前预防的 57 名青少年和 25 名临床医生进行的定性研究。在青少年群体中，3%的人使用过非处方 ART，14%的人知道有人出于娱乐目的使用非处方 ART。他们使用 ART 的方式包括吸食（71%）、鼻吸（15%）、注射（15%）、口服（15%）和插入（3%）。参与者预测随着 ART 被滥用于娱乐用途的增加，犯罪率将会上升。未来的研究应调查从 HIV 预防和治疗中转移出来的 ART 的使用情况、组成和滥用情况。
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