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The HIV antiretroviral drug efavirenz has LSD-like properties.HIV 抗逆转录病毒药物依非韦伦具有 LSD 样特性。
Neuropsychopharmacology. 2013 Nov;38(12):2373-84. doi: 10.1038/npp.2013.135. Epub 2013 May 24.
2
Pretreatment antiretroviral exposure from recreational use.因娱乐用途而进行的抗逆转录病毒药物预处理暴露。
Lancet Infect Dis. 2013 Jan;13(1):10-2. doi: 10.1016/S1473-3099(12)70294-3.
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HIV drug resistance (HIVDR) in antiretroviral therapy-naïve patients in Tanzania not eligible for WHO threshold HIVDR survey is dramatically high.在坦桑尼亚,未接受过抗逆转录病毒治疗的患者中,不符合世界卫生组织耐药阈值调查标准的 HIV 耐药(HIVDR)比例非常高。
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Impact of non-HIV and HIV risk factors on survival in HIV-infected patients on HAART: a population-based nationwide cohort study.非 HIV 和 HIV 风险因素对接受高效抗逆转录病毒治疗的 HIV 感染患者生存的影响:一项基于人群的全国性队列研究。
PLoS One. 2011;6(7):e22698. doi: 10.1371/journal.pone.0022698. Epub 2011 Jul 25.
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Lancet. 2010 Jul 31;376(9738):355-66. doi: 10.1016/S0140-6736(10)60832-X.
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Patterns of substance use in South Africa: results from the South African Stress and Health study.南非的物质使用模式:来自南非压力与健康研究的结果。
S Afr Med J. 2009 May;99(5 Pt 2):358-66.
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Adherence to antiretroviral therapy among HIV-infected drug users: a meta-analysis.HIV 感染者中药物使用者对抗逆转录病毒治疗的依从性:一项荟萃分析。
AIDS Behav. 2010 Aug;14(4):731-47. doi: 10.1007/s10461-008-9489-7. Epub 2008 Nov 20.
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The association between HIV infection and alcohol use: a systematic review and meta-analysis of African studies.艾滋病毒感染与酒精使用之间的关联:对非洲研究的系统评价和荟萃分析。
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10
Alcohol use and sexual risks for HIV/AIDS in sub-Saharan Africa: systematic review of empirical findings.撒哈拉以南非洲地区酒精使用与艾滋病毒/艾滋病的性传播风险:实证研究结果的系统评价
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南非:潜在的 HIV 抗逆转录病毒药物的娱乐性使用

Whoonga: potential recreational use of HIV antiretroviral medication in South Africa.

机构信息

Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA,

出版信息

AIDS Behav. 2014 Mar;18(3):511-8. doi: 10.1007/s10461-013-0575-0.

DOI:10.1007/s10461-013-0575-0
PMID:23955659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3926908/
Abstract

Whoonga is a drug cocktail in South Africa rumored to contain illicit drugs and HIV antiretroviral (ARV) medication. Although its use may adversely impact adherence to HIV treatment and may have the potential to generate ARV resistance, there is a paucity of research characterizing whoonga. We learned of whoonga during semi-structured interviews about substance abuse and HIV risk at "club-events" known as inkwaris in an urban township of Durban, South Africa. Whoonga was an emerging theme spontaneously identified as a problem for the community by 17 out of 22 informants. Perceptions of whoonga suggest that it is highly addictive, contains ARVs (notably efavirenz), is used by individuals as young as 14, and poses a threat to the health and safety of those who use it, including increasing the risk of HIV infection. Our informants provide preliminary evidence of the dangers of whoonga and reinforce the need for further study.

摘要

“嗡嗡嗡”是一种在南非流行的毒品混合物,据传言称其含有非法药物和艾滋病抗逆转录病毒(ARV)药物。尽管其使用可能会对艾滋病治疗的依从性产生不利影响,并可能具有产生抗逆转录病毒耐药性的潜力,但目前针对“嗡嗡嗡”的研究还很少。我们是在对南非德班市一个城镇的“俱乐部活动”中的药物滥用和艾滋病风险进行半结构化访谈时了解到“嗡嗡嗡”的。在 22 名受访者中,有 17 人自发地将“嗡嗡嗡”确定为社区的一个问题,这一主题开始浮现。人们对“嗡嗡嗡”的看法表明,它具有很强的成瘾性,含有 ARV(特别是依非韦伦),14 岁以下的人也在使用,这对使用者的健康和安全构成了威胁,包括增加感染艾滋病的风险。我们的受访者提供了“嗡嗡嗡”危险的初步证据,并强调需要进一步研究。