Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.
Landeslabor Berlin-Brandenburg (LLBB), 15236 Frankfurt (Oder), Germany.
Viruses. 2020 Mar 4;12(3):281. doi: 10.3390/v12030281.
A novel H5N8 highly pathogenic avian influenza virus (HPAIV) was detected in a greater white-fronted goose in January 2020 in Brandenburg, Germany, and, in February 2020, in domestic chickens belonging to a smallholding in Baden-Wuerttemberg, Germany. Full-genome sequencing was conducted on the MinION platform, enabling further phylogenetic analyses. The virus of clade 2.3.4.4b holds six segments from a Eurasian/Asian/African HPAIV H5N8 reassortant and two segments from low pathogenic avian influenza H3N8 subtype viruses recently detected in wild birds in Central Russia. These new entries continue to show the reassortment potential of the clade 2.3.4.4 H5Nx viruses, underlining the necessity for full-genome sequencing and continuous surveillance.
2020 年 1 月，德国勃兰登堡州一只大额头鹅中检测到一种新型 H5N8 高致病性禽流感病毒（HPAIV），2020 年 2 月，德国巴登-符腾堡州一个小型农场的家鸡中也检测到这种病毒。对 MinION 平台上的全基因组进行测序，从而能够进行进一步的系统发育分析。该病毒属于 2.3.4.4b 分支，包含六个来自欧亚/亚洲/非洲 HPAIV H5N8 重组病毒的片段，以及两个来自最近在俄罗斯中部野生鸟类中检测到的低致病性禽流感 H3N8 亚型病毒的片段。这些新的病毒株继续显示出 2.3.4.4 H5Nx 病毒的重组潜力，这凸显了全基因组测序和持续监测的必要性。
