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黄芪中化学成分抗衰老作用机制的实验与临床研究(综述)

[Experimental and clinical studies of mechanisms of the anti-aging effects of chemical compounds in Astragalus membranaceus (review).].

作者信息

Berezutsky M A, Durnova N A, Vlasova I A

机构信息

V.I.Razumovsky Saratov State Medical University, 112 Bol'shaya Kazach'ya str., Saratov 410012, Russian Federation, e-mail:

出版信息

Adv Gerontol. 2019;32(5):702-710.

Abstract

Astragalus membranaceus (webbed astragalus) for more than two millennia has been used in traditional Chinese medicine as a means of slowing down the aging process and increasing longevity. The article analyzes the data of experimental and clinical studies of recent years, identifying possible mechanisms of the anti-aging effects of the plant. It is noted that the extract or various groups of chemical compounds of this plant activate telomerase, inhibit the processes of replicative senescence, have antioxidant activity, have a neuroprotective effect, affect age-related macular degeneration, skin photoaging and alopecia.

摘要

两千多年来,黄芪一直被用于传统中医,作为延缓衰老过程和延长寿命的一种手段。本文分析了近年来的实验和临床研究数据,确定了该植物抗衰老作用的可能机制。值得注意的是,这种植物的提取物或各类化合物能激活端粒酶,抑制复制性衰老过程,具有抗氧化活性,具有神经保护作用,影响年龄相关性黄斑变性、皮肤光老化和脱发。

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