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更年期和衰老对法国女性脊柱骨密度的影响。

Influence of the menopause and aging on spinal density in French women.

作者信息

Ribot C, Tremollieres F, Pouilles J M, Louvet J P, Guiraud R

机构信息

Department of Endocrinology, Centre Hospitalier Purpan, Toulouse, France.

出版信息

Bone Miner. 1988 Oct;5(1):89-97. doi: 10.1016/0169-6009(88)90009-8.

DOI:10.1016/0169-6009(88)90009-8
PMID:3214683
Abstract

Dual photon absorptiometry (DPA) was used to measure the bone mineral density (BMD) of the lumbar spine in 510 normal women from the south of France. Long-term precision was 2.2%. BMD was stable in young adults and again in women over 70 years of age. Perimenopausal women at an average age of 51 years already evidenced a slight bone diminution (5%) compared to young adults and women within 2 years of the menopause already had a 10% diminution. The average rate of apparent bone loss in this cross-sectional study was 1% per year from age 45 to 65 years, but about 75% of this decrease occurred in the first decade after the menopause. Spinal BMD in our normal French population appears to be 5-10% lower than US values.

摘要

采用双能光子吸收法(DPA)测量了来自法国南部的510名正常女性腰椎的骨密度(BMD)。长期精密度为2.2%。骨密度在年轻成年人以及70岁以上女性中保持稳定。平均年龄51岁的围绝经期女性与年轻成年人相比已出现轻微骨质减少(5%),而绝经后2年内的女性骨质减少达10%。在这项横断面研究中,45至65岁期间明显骨质流失的平均速率为每年1%,但其中约75%的减少发生在绝经后的第一个十年。我们法国正常人群的脊柱骨密度似乎比美国人群低5% - 10%。

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