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器质性遗忘症中额叶功能障碍的双重分离

Double dissociation of frontal dysfunction in organic amnesia.

作者信息

Leng N R, Parkin A J

机构信息

Laboratory of Experimental Psychology, University of Sussex, Brighton, UK.

出版信息

Br J Clin Psychol. 1988 Nov;27(4):359-62. doi: 10.1111/j.2044-8260.1988.tb00800.x.

DOI:10.1111/j.2044-8260.1988.tb00800.x
PMID:3214689
Abstract

Subjects with either diencephalic or bilateral medial temporal lobe amnesia were examined on the Wisconsin Card Sorting Test (WCST) and Cognitive Estimation Test (CET). Alcoholic Korsakoff patients performed more poorly on the WCST but normally on the CET, whereas post-encephalitic patients performed normally on the WCST but poorly on the CET. This double dissociation is interpreted as reflecting different patterns of frontal dysfunction in Korsakoff and post-encephalitic amnesia.

摘要

对患有间脑性或双侧内侧颞叶失忆症的受试者进行了威斯康星卡片分类测试(WCST)和认知估计测试(CET)。酒精所致柯萨科夫综合征患者在WCST上表现较差,但在CET上表现正常,而脑炎后患者在WCST上表现正常,但在CET上表现较差。这种双重分离被解释为反映了柯萨科夫综合征和脑炎后失忆症中额叶功能障碍的不同模式。

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