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李斯特菌病的当前研究进展

Current aspects of listeriosis.

作者信息

Lepe José Antonio

机构信息

Unidad Clínica de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, Sevilla, España.

出版信息

Med Clin (Barc). 2020 Jun 12;154(11):453-458. doi: 10.1016/j.medcli.2020.02.001. Epub 2020 Mar 5.

DOI:10.1016/j.medcli.2020.02.001
PMID:32147188
Abstract

The importance of listeriosis is not sufficiently recognised. The general incidence of infection has been stable in recent years, but with an upward trend in people over 65, also in mortality. Listeriosis is a foodborne disease that generally occurs in the form of sporadic cases; however, new molecular typing techniques have revealed the existence of epidemic outbreaks not previously suspected. The disease has a variable incubation period, which is related to the clinical presentation. Bacteraemia and neurolisteriosis are the predominant clinical forms, although at present, the main interest is focused on the management of focal infections and those associated with prosthetic devices. Listeriosis is a significant problem for the food industry, and many countries have introduced legislation to control the incidence of the disease.

摘要

李斯特菌病的重要性尚未得到充分认识。近年来,感染的总体发病率一直稳定,但65岁以上人群的发病率呈上升趋势,死亡率也呈上升趋势。李斯特菌病是一种食源性疾病,通常以散发病例的形式出现;然而,新的分子分型技术揭示了以前未被怀疑的疫情爆发的存在。该病的潜伏期长短不一,与临床表现有关。菌血症和神经型李斯特菌病是主要的临床形式,尽管目前主要关注的是局部感染和与假体装置相关的感染的管理。李斯特菌病对食品工业来说是一个重大问题,许多国家已出台立法以控制该病的发病率。

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