与异丙肾上腺素气雾剂和安慰剂气雾剂相比，沙丁胺醇气雾剂的剂量-反应效应：对沙丁胺醇、异丙肾上腺素和安慰剂气雾剂的反应
Dose-response effects of albuterol aerosol compared with isoproterenol and placebo aerosols: response to albuterol, isoproterenol, and placebo aerosols.
作者信息
Spector S L, Garza Gomez M
出版信息
J Allergy Clin Immunol. 1977 Apr;59(4):280-6. doi: 10.1016/0091-6749(77)90048-3.
Albuterol aerosol was an effective bronchodilator as reflected by indices of pulmonary function obtained from spirometry and flow volume curves; Compared with isoproterenol, there were minimal side effects even at the highest doses, and bronchodilation lasted significantly longer. In addition albuterol was successfully used by a patient with idiopathic hypertrophic subaortic stenosis who was unable to tolerate isoproterenol, as well as by some patients with idiosyncratic responses to isoproterenol; A few patients appeared to derive little benefit from either albuterol or isoproterenol.
沙丁胺醇气雾剂是一种有效的支气管扩张剂，这一点从肺活量测定和流量容积曲线所获得的肺功能指标可以看出；与异丙肾上腺素相比，即使在最高剂量时副作用也极小，而且支气管扩张持续时间明显更长。此外，一名患有特发性肥厚性主动脉瓣下狭窄且无法耐受异丙肾上腺素的患者以及一些对异丙肾上腺素产生特异反应的患者成功使用了沙丁胺醇；少数患者似乎从沙丁胺醇或异丙肾上腺素中获益甚微。
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