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利用放疗优化来对抗放射抵抗。

Counteracting Radio-Resistance Using the Optimization of Radiotherapy.

机构信息

UMR6252 CIMAP, CEA-CNRS-ENSICAEN-Université de Caen Normandie, 14000 Caen, France.

LARIA, iRCM, François Jacob Institute, DRF-CEA, 14000 Caen, France.

出版信息

Int J Mol Sci. 2020 Mar 5;21(5):1767. doi: 10.3390/ijms21051767.

DOI:10.3390/ijms21051767
PMID:32150868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7084332/
Abstract

Radiotherapy is an essential component of cancer therapy and remains one of the most (cost-) effective treatment options available [...].

摘要

放射治疗是癌症治疗的重要组成部分，也是目前最具（成本）效益的治疗方法之一[... ]。

相似文献

1
Counteracting Radio-Resistance Using the Optimization of Radiotherapy.利用放疗优化来对抗放射抵抗。
Int J Mol Sci. 2020 Mar 5;21(5):1767. doi: 10.3390/ijms21051767.
2
Normal tissue tolerance to intraoperative radiation therapy. Experimental and clinical studies.正常组织对术中放射治疗的耐受性。实验与临床研究。
Front Radiat Ther Oncol. 1989;23:202-14. doi: 10.1159/000416584.
3
Clinical radiation tolerance of brain, spinal cord, and peripheral nerves. Laboratory and patient data as clinical guides.
Front Radiat Ther Oncol. 1989;23:367-89. doi: 10.1159/000416598.
4
Feasibility of using internal radiation-generating devices in radiotherapy.在放射治疗中使用内辐射发生装置的可行性。
Health Phys. 2010 Apr;98(4):614-20. doi: 10.1097/HP.0b013e3181c8f6ac.
5
[Delineation of organs at risk and dose constraints].[危及器官的勾画与剂量限制]
Cancer Radiother. 2016 Sep;20 Suppl:S36-60. doi: 10.1016/j.canrad.2016.07.032. Epub 2016 Aug 8.
6
Optimization of radiotherapy. Report of a WHO meeting of investigators.放射治疗的优化。世界卫生组织研究者会议报告。
World Health Organ Tech Rep Ser. 1980;644:1-89.
7
The determination of the radio-sensitivity of tumours.肿瘤放射敏感性的测定
Ir J Med Sci. 1961 Nov;431:475-86. doi: 10.1007/BF02953742.
8
Complications from radiation therapy to the eye.眼部放射治疗的并发症。
Front Radiat Ther Oncol. 1989;23:238-50; discussion 251-4. doi: 10.1159/000416587.
9
[The radiotherapy journey: from information to treatment].放疗历程：从信息到治疗
Rev Med Liege. 2014;69 Suppl 1:3-8.
10
[Approximate methods for calculation of the likelihood of radiation complications. The generalized PKLQ method (GPKLQM)].
Med Tekh. 2002 Sep-Oct(5):27-32.

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Particle Therapy to Overcome Cancer Radiation Resistance: "ARCHADE" Consortium Updates in Radiation Biology.粒子疗法克服癌症辐射抗性：“ARCHADE”联盟在放射生物学方面的进展
Cancers (Basel). 2025 May 6;17(9):1580. doi: 10.3390/cancers17091580.
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[Research Progress of Engineered Exosomes in the Treatment of Lung Cancer].[工程化外泌体治疗肺癌的研究进展]
Zhongguo Fei Ai Za Zhi. 2024 Jul 20;27(7):535-540. doi: 10.3779/j.issn.1009-3419.2024.101.17.
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Potential Benefits of Combining Proton or Carbon Ion Therapy with DNA Damage Repair Inhibitors.质子或碳离子治疗联合 DNA 损伤修复抑制剂的潜在获益。
Cells. 2024 Jun 19;13(12):1058. doi: 10.3390/cells13121058.
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Application of nanotechnology in reversing therapeutic resistance and controlling metastasis of colorectal cancer.纳米技术在逆转结直肠癌治疗抵抗和控制转移中的应用。
World J Gastroenterol. 2023 Apr 7;29(13):1911-1941. doi: 10.3748/wjg.v29.i13.1911.
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Engineered exosomes from different sources for cancer-targeted therapy.不同来源的工程化细胞外囊泡用于癌症靶向治疗。
Signal Transduct Target Ther. 2023 Mar 15;8(1):124. doi: 10.1038/s41392-023-01382-y.
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Radiotherapy prognosis-associated gene GCNT3 promotes the proliferation, migration and invasion of lung adenocarcinoma cells.放疗预后相关基因GCNT3促进肺腺癌细胞的增殖、迁移和侵袭。
Heliyon. 2022 Dec 7;8(12):e12100. doi: 10.1016/j.heliyon.2022.e12100. eCollection 2022 Dec.
7
in cancer: Potential role in regulating MicroRNAs and epigenetic enzymes.在癌症中：在调节微小RNA和表观遗传酶方面的潜在作用。
Front Pharmacol. 2022 Sep 12;13:1008222. doi: 10.3389/fphar.2022.1008222. eCollection 2022.

本文引用的文献

1
TiO Nanomaterials Non-Controlled Contamination Could Be Hazardous for Normal Cells Located in the Field of Radiotherapy.TiO2 纳米材料的非受控污染可能对放射治疗场中正常细胞造成危害。
Int J Mol Sci. 2020 Jan 31;21(3):940. doi: 10.3390/ijms21030940.
2
Hadrontherapy Interactions in Molecular and Cellular Biology.强子疗法在分子和细胞生物学中的相互作用。
Int J Mol Sci. 2019 Dec 24;21(1):133. doi: 10.3390/ijms21010133.
3
FGFR Signaling as a Candidate Therapeutic Target for Cancers Resistant to Carbon Ion Radiotherapy.成纤维细胞生长因子受体信号作为抵抗碳离子放射治疗的癌症的候选治疗靶点。
Int J Mol Sci. 2019 Sep 14;20(18):4563. doi: 10.3390/ijms20184563.
4
Robustness of Clonogenic Assays as a Biomarker for Cancer Cell Radiosensitivity.克隆集落形成分析作为癌症细胞放射敏感性生物标志物的稳健性。
Int J Mol Sci. 2019 Aug 25;20(17):4148. doi: 10.3390/ijms20174148.
5
Radiosensitivity Differences between Mutant and Wild-Type Lung Cancer Cells are Larger at Lower Doses.突变型和野生型肺癌细胞的放射敏感性差异在较低剂量时更大。
Int J Mol Sci. 2019 Jul 25;20(15):3635. doi: 10.3390/ijms20153635.