Muszyński Siemowit, Dobrowolski Piotr, Kasperek Kornel, Knaga Sebastian, Kwiecień Małgorzata, Donaldson Janine, Kutyła Mateusz, Kapica Małgorzata, Tomaszewska Ewa
Department of Biophysics, Faculty of Environmental Biology, University of Life Sciences in Lublin, Akademicka St. 13, 20-950 Lublin, Poland.
Department of Functional Anatomy and Cytobiology, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Animals (Basel). 2020 Mar 5;10(3):440. doi: 10.3390/ani10030440.
The aim of the study was to investigate the changes in bone geometry, histological structure, and selected mechanical characteristics in young male and female Japanese quails supplemented with . Quails were fed a basal diet containing no yeast or a basal diet supplemented with 1.5% (15 g per 1 kg of diet) of inactive , for a period of 42 days. inclusion had no effect on bone weight, length, and density, diaphysis geometry (cross-sectional area, wall thickness, moment of inertia) or on the mechanical strength (yield load, ultimate load, stiffness, Young's modulus, yield stress, ultimate stress). Yeast supplementation improved the morphology of the articular cartilage both in male and female quails, as the total thickness of the articular cartilage was significantly increased. In trabecular bone, an increase in real bone volume and trabecular thickness was observed in females supplemented with , while in males the increase in trabecular number was accompanied by a reduction in trabecular thickness. The results of the present study demonstrate that , through a sex-dependent action on the gut-bone axis, improved the structure of articular cartilage and microarchitecture of trabecular bone. The positive effects of supplementation were more evident in female quails.
本研究的目的是调查补充了[具体物质]的年轻日本雄性和雌性鹌鹑的骨骼几何形状、组织结构以及选定的力学特性的变化。鹌鹑被喂食不含酵母的基础日粮或补充了1.5%（每1千克日粮含15克）非活性[具体物质]的基础日粮，为期42天。补充[具体物质]对骨骼重量、长度和密度、骨干几何形状（横截面积、壁厚、惯性矩）或力学强度（屈服载荷、极限载荷、刚度、杨氏模量、屈服应力、极限应力）没有影响。补充酵母改善了雄性和雌性鹌鹑关节软骨的形态，因为关节软骨的总厚度显著增加。在松质骨中，补充[具体物质]的雌性鹌鹑的真实骨体积和小梁厚度增加，而在雄性鹌鹑中，小梁数量增加的同时小梁厚度减少。本研究结果表明，[具体物质]通过对肠-骨轴的性别依赖性作用，改善了关节软骨结构和松质骨微结构。补充[具体物质]的积极作用在雌性鹌鹑中更为明显。
