Nederlandse Obesitas Kliniek (Dutch Obesity Clinic), Huis ter Heide, The Netherlands.
Nederlandse Obesitas Kliniek, Postbus 601, 3700 AP, Zeist, The Netherlands.
Qual Life Res. 2020 Jul;29(7):1847-1854. doi: 10.1007/s11136-020-02449-x. Epub 2020 Mar 9.
Sleeve gastrectomy (SG) is the most popular type of bariatric surgery. It has often been compared to Roux-en-Y gastric bypass (RYGB) in terms of clinical outcomes. However, health-related quality of life (HRQoL) has been sparsely studied after SG. The goal was to study HRQoL after SG using a generic (RAND-36) and an obesity-specific (impact of weight on quality of life-lite, IWQOL-lite) questionnaire and to compare the results with RYGB.
HRQoL and weight were measured before and 9, 15, and 24 months after surgery. RAND-36 physical health summary (PHS) and mental health summary (MHS), and IWQOL-lite total score were calculated. A mixed model analysis was conducted to study the change in HRQoL and compare SG with RYGB.
A total of 219 patients (8.7%) underwent a SG and 2309 patients (91.3%) a RYGB. PHS, MHS, and IWQOL-lite significantly improved after SG when comparing baseline to all follow-up moments (p < 0.001 in all). There were no significant differences when comparing SG with RYGB: change in PHS (β - 0.10, 95% CI - 1.24 to 1.04, p = 0.861), MHS (β - 0.51, 95% CI - 1.56 to 0.52, p = 0.330), and IWQOL-lite (β 0.310, 95% CI - 0.85 to 1.47, p = 0.601).
HRQoL significantly improved after SG. In the included populations, weight loss was comparable and the extent to which HRQoL improved did not differ between SG and RYGB, when measured with the RAND-36 or IWQOL-lite. This might be partly caused by the fact that these questionnaires do not assess specific bariatric HRQoL and/or complaints.
袖状胃切除术（SG）是最受欢迎的减肥手术类型。它在临床结果方面经常与 Roux-en-Y 胃旁路术（RYGB）进行比较。然而，SG 后的生活质量（HRQoL）研究甚少。本研究的目的是使用通用（RAND-36）和肥胖特定（体重对生活质量的影响-lite，IWQOL-lite）问卷研究 SG 后的 HRQoL，并将结果与 RYGB 进行比较。
在手术前和手术后 9、15 和 24 个月测量 HRQoL 和体重。计算 RAND-36 身体健康综合评分（PHS）和心理健康综合评分（MHS）以及 IWQOL-lite 总分。采用混合模型分析研究 HRQoL 的变化，并比较 SG 与 RYGB。
共有 219 例患者（8.7%）接受了 SG，2309 例患者（91.3%）接受了 RYGB。与基线相比，SG 后 PHS、MHS 和 IWQOL-lite 均显著改善（所有 p 值均<0.001）。SG 与 RYGB 之间没有显著差异：PHS 变化（β-0.10，95%CI-1.24 至 1.04，p=0.861）、MHS 变化（β-0.51，95%CI-1.56 至 0.52，p=0.330）和 IWQOL-lite 变化（β0.310，95%CI-0.85 至 1.47，p=0.601）。
SG 后 HRQoL 显著改善。在纳入的人群中，SG 和 RYGB 的减重效果相当，且 RAND-36 或 IWQOL-lite 测量的 HRQoL 改善程度没有差异。这可能部分是由于这些问卷没有评估特定的减肥手术 HRQoL 和/或投诉。
