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减重手术后生活质量的改善:袖状胃切除术与旁路手术。

Improvement in quality of life after bariatric surgery: sleeve versus bypass.

机构信息

Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.

Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.

出版信息

Surg Obes Relat Dis. 2018 Feb;14(2):170-174. doi: 10.1016/j.soard.2017.10.008. Epub 2017 Oct 16.

DOI:10.1016/j.soard.2017.10.008
PMID:29150392
Abstract

BACKGROUND

Obesity is steadily growing to be the largest threat to human health in this century, not only increasing prevalence of obesity-related co-morbidity but also impairing health-related quality of life (QoL). Bariatric surgery has shown to improve co-morbidity as well as QoL.

OBJECTIVES

To assess the differences in improvement in QoL for the 2 most performed procedures: laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux-en-Y gastric bypass (RYGB).

SETTING

Obesity center, the Netherlands.

METHODS

All patients who underwent either SG or RYGB as a primary operation from January 2012 until January 2017 were eligible. Included, were only those who completed preoperatively and 1-year postoperatively the QoL questionnaire. The RAND 36-item Health Survey was used to assess QoL.

RESULTS

A total of 1184 cases were included in analysis of which 666 patients underwent SG and 518 patients underwent RYGB. Groups significantly differed in body mass index, weight, waist circumference, prevalence of gastroesophageal reflux disease, obstructive sleep apnea syndrome, and hypertension. All QoL domains greatly improved after bariatric surgery. Physical functioning increased more in patients who underwent gastric bypass. This remained significant after correcting for differences between groups. Other domains were not significantly different.

CONCLUSION

QoL is greatly improved at 1 year after bariatric surgery. The improvement was comparable after SG and RYGB, expect for more increase in physical functioning after RYGB. QoL could influence decision-making between SG and RYGB. So far, no clinically relevant differences were found. Future research should focus on both longer follow-up and more specific questionnaires.

摘要

背景

肥胖正稳步成为本世纪对人类健康的最大威胁,不仅增加了肥胖相关合并症的患病率,还降低了健康相关生活质量(QoL)。减重手术已被证明可以改善合并症和 QoL。

目的

评估两种最常施行的手术(腹腔镜袖状胃切除术(SG)和腹腔镜 Roux-en-Y 胃旁路术(RYGB))在 QoL 改善方面的差异。

设置

荷兰肥胖中心。

方法

所有于 2012 年 1 月至 2017 年 1 月间接受 SG 或 RYGB 作为初次手术的患者均符合入选标准。仅纳入那些术前和术后 1 年完成 QoL 问卷的患者。采用 RAND 36 项健康调查量表评估 QoL。

结果

共有 1184 例患者纳入分析,其中 666 例患者接受 SG,518 例患者接受 RYGB。两组在体重指数、体重、腰围、胃食管反流病、阻塞性睡眠呼吸暂停综合征和高血压的患病率方面存在显著差异。减重手术后所有 QoL 领域均显著改善。胃旁路术后患者的身体机能改善更为显著。在对两组间的差异进行校正后,这种差异仍然显著。其他领域无显著差异。

结论

减重手术后 1 年 QoL 得到显著改善。SG 和 RYGB 术后改善情况相当,但 RYGB 术后身体机能的改善更为明显。QoL 可能影响 SG 和 RYGB 之间的决策。目前尚未发现具有临床意义的差异。未来的研究应侧重于更长时间的随访和更具体的问卷。

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