Fasseeh Ahmad, Karam Rita, Jameleddine Mouna, George Mohsen, Kristensen Finn Børlum, Al-Rabayah Abeer A, Alsaggabi Abdulaziz H, El Rabbat Maha, Alowayesh Maryam S, Chamova Julia, Ismail Adham, Abaza Sherif, Kaló Zoltán
Doctoral School of Sociology, Faculty of Social Sciences, Eötvös Loránd University Budapest, Budapest, Hungary.
Syreon Middle East, Alexandria, Egypt.
Front Pharmacol. 2020 Feb 21;11:15. doi: 10.3389/fphar.2020.00015. eCollection 2020.
Implementation of health technology assessment (HTA) is still in an early stage with some heterogeneity in the Middle East and North Africa (MENA). Our objective was to assess the current and future status of HTA implementation in the MENA region by focusing on regional commonalities.
Preparatory discussions for the first ISPOR conference in the MENA region indicated some potentially generalizable trends of HTA roadmaps. To widen the perspective, a policy survey was conducted among conference participants by applying an HTA implementation scorecard. Discussion group members helped to validate key conclusions during and after the conference.
Health policy experts in MENA countries would like to facilitate HTA implementation and expect significant changes with some generalizable directions in 10 years compared to the current status according. HTA capacity building has to be strengthened by more graduate and postgraduate programs. Increased public budget and enhanced institutionalization are necessary success factors of HTA implementation. The scope of HTA has to be extended from pharmaceuticals to non-pharmaceutical technologies and to revision of previous policy decisions. Although cost-effectiveness with explicit threshold remains the most preferred HTA criterion, several other criteria have to be considered, maybe even by applying an explicit MCDA framework. The role of local evidence and data has to be strengthened in MENA countries, which translates to the extended use of local patient registries and payers' databases. Duplication of efforts can be reduced if international collaboration is integrated into national HTA implementation.
Our results should be viewed as an initial step in a multi-stakeholder dialogue on HTA implementation. Each MENA country should develop its context-specific HTA roadmap, as such roadmaps are not transferable without taking into account country size, economic status, public health priorities and adopted systems of health care financing.
中东和北非(MENA)地区卫生技术评估(HTA)的实施仍处于早期阶段,存在一定的异质性。我们的目标是通过关注区域共性来评估HTA在中东和北非地区的当前及未来实施状况。
中东和北非地区首届国际药物经济学与结果研究协会(ISPOR)会议的筹备讨论表明了HTA路线图的一些潜在可推广趋势。为拓宽视野,通过应用HTA实施记分卡对会议参与者进行了政策调查。讨论组成员在会议期间及会后协助验证关键结论。
中东和北非国家的卫生政策专家希望推动HTA的实施,并预计与当前状况相比,10年后会有一些可推广方向的重大变化。必须通过更多的研究生和博士后项目来加强HTA能力建设。增加公共预算和加强制度化是HTA实施的必要成功因素。HTA的范围必须从药品扩展到非药品技术,并对先前的政策决定进行修订。尽管具有明确阈值的成本效益仍然是最受青睐的HTA标准,但还必须考虑其他一些标准,甚至可能需要应用明确的多标准决策分析(MCDA)框架。在中东和北非国家,必须加强本地证据和数据的作用,这意味着要扩大本地患者登记册和支付方数据库的使用。如果将国际合作纳入国家HTA实施中,可以减少工作的重复。
我们的结果应被视为关于HTA实施的多利益相关方对话的第一步。每个中东和北非国家都应制定其特定背景的HTA路线图,因为如果不考虑国家规模、经济状况、公共卫生优先事项和采用的医疗保健融资系统,此类路线图是不可转让的。