Zillmer Krista, Pokharel Ashish, Spielman Kathryn, Kershaw Meghan, Ayele Kidane, Kidane Yitbarek, Belachew Tefera, Houser Robert F, Kennedy Eileen, Griffiths Jeffrey K, Ghosh Shibani
1Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, 150 Harrison Ave, Boston, MA 02111 USA.
2Jimma University, 378 Jimma, Ethiopia.
BMC Nutr. 2017 Jul 25;3:65. doi: 10.1186/s40795-017-0166-y. eCollection 2017.
Anemia in pregnancy is associated with higher risk of low birth weight and both maternal and perinatal mortality. While previous studies in Ethiopia have examined factors associated with anemia, which factors are the most important determinants of anemia in this population remain unclear. The objective of this study was to examine the association between anemia status in pregnant women with different health, behavioral, and socioeconomic factors in Oromiya province of Ethiopia.
This study used pregnancy enrollment data from a longitudinal birth cohort study conducted in Ethiopia. Survey data on maternal and household characteristics were collected at enrollment and maternal hemoglobin levels were measured. The analysis includes 4600 pregnant women. Logistic regression models were used to identify factors associated with maternal anemia in pregnancy.
Controlling for geographic location and religion, low maternal MUAC and previous pregnancies were associated with increased odds of anemia, with odds ratios of 1.30 ( < 0.001, CI 1.12-1.51), and 1.50 ( = 0.002, CI 1.16-1.95), respectively. For each additional point on the handwashing score scale, the odds of being anemic were reduced by 12% ( < 0.001, CI 0.82-0.94). Numerate women compared to non-numerate women had 30% lower odds ( < 0.001, CI 0.57-0.85).
Controlling for woreda and religion, low maternal MUAC, and previous pregnancy increased odds of anemia while numeracy and better handwashing practices significantly reduced the odds of anemia in pregnancy. Further investigation is needed to determine the cause of anemia in pregnant women in Oromiya and to determine the effects of maternal anemia on birth outcomes.
妊娠期贫血与低出生体重以及孕产妇和围产期死亡风险增加相关。虽然埃塞俄比亚此前的研究已探讨了与贫血相关的因素,但在该人群中哪些因素是贫血的最重要决定因素仍不清楚。本研究的目的是在埃塞俄比亚奥罗米亚州探讨孕妇贫血状况与不同健康、行为和社会经济因素之间的关联。
本研究使用了埃塞俄比亚一项纵向出生队列研究中的妊娠登记数据。在登记时收集了产妇和家庭特征的调查数据,并测量了产妇血红蛋白水平。分析纳入了4600名孕妇。采用逻辑回归模型确定与妊娠期孕产妇贫血相关的因素。
在控制地理位置和宗教因素后,产妇低上臂中段臂围(MUAC)和既往妊娠与贫血几率增加相关,比值比分别为1.30(P<0.001,可信区间1.12 - 1.51)和1.50(P = 0.002,可信区间1.16 - 1.95)。洗手评分量表每增加一分,贫血几率降低12%(P<0.001,可信区间0.82 - 0.94)。识字女性与不识字女性相比,贫血几率低30%(P<0.001,可信区间0.57 - 0.85)。
在控制行政区和宗教因素后,产妇低MUAC和既往妊娠会增加贫血几率,而识字和更好的洗手习惯可显著降低妊娠期贫血几率。需要进一步调查以确定奥罗米亚州孕妇贫血的原因,并确定孕产妇贫血对出生结局的影响。