三叶崖爬藤A，一种来自（毛枝崖爬藤邓恩）J.F.麦克布赖德的具有生物学特性的新型化合物。

Triculata A, a novel compound from (D. Don) J. F. Macbr. with biological properties.

作者信息

Ren Li, Wang Yun-Ze, Zhang Wei, Zhou Rui, Zhao Ming, Tang Zhi-Shu, Sun Jing, Zhang Dong-Bo

机构信息

Shaanxi Collaborative Innovation Center of Chinese Medicine Resources Industrialization, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Innovative Drug Research Center, Shaanxi University of Chinese Medicine, Xianyang, P.R. China.

Department of Basic Medicine, Xi'an Jiaotong University, Xi'an, P.R. China.

出版信息

Nat Prod Res. 2021 Nov;35(21):3729-3737. doi: 10.1080/14786419.2020.1736059. Epub 2020 Mar 10.

DOI:10.1080/14786419.2020.1736059

PMID:32154735

Abstract

A novel compound, triculata A (), and seven known compounds were obtained from the (D. Don) J. F. Macbr.. The structure of the new compound was determined by extensive spectroscopic methods, and its absolute configuration was assigned by single-crystal X-ray diffraction analysis. Compound features a rare naphtho[]pyran carbon skeleton that was found in nature for the first time. Compounds , and showed potential vasodilatory effects with EC values ranging from 7.3 to 111.3 M. Compounds , and possessed remarkable antioxidant capacity evaluated by DPPH and ABTS assays.

摘要

从（D. Don）J. F. Macbr.中获得了一种新型化合物三叶草素A（）和七种已知化合物。通过广泛的光谱方法确定了新化合物的结构，并通过单晶X射线衍射分析确定了其绝对构型。化合物具有罕见的萘并[]吡喃碳骨架，这是首次在自然界中发现。化合物、和显示出潜在的血管舒张作用，其EC值范围为7.3至111.3μM。通过DPPH和ABTS测定评估，化合物、和具有显著的抗氧化能力。