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有缺陷的科学研究阻碍了进展,造成了混乱。

Flawed scientific studies block progress and sow confusion.

出版信息

GM Crops Food. 2020 Jul 2;11(3):125-129. doi: 10.1080/21645698.2020.1737482. Epub 2020 Mar 10.

Abstract

Research in crop science in recent years has advanced at an unprecedented rate, and the intermingling of old and new crop breeding technologies has made the term "genetically modified" - and its variant, Genetically Modified Organism, or "GMO" - virtually obsolete. A kind of pseudo-category, it is primarily used pejoratively to refer to the use of the newest, most precise, most predictable, molecular genetic techniques. Prodigious amounts of time, effort and care have been expended to ensure that crops developed for commercialization using molecular techniques are safe, and that new traits are beneficial. Â Yet, despite these advances, some skepticism persists about them, partly due to the publication of fraudulent, poorly designed, and biased studies by a few "rogue scientists" whose intention is to contaminate the scientific literature and sow mistrust about molecular genetic modification among regulators and the public. We discuss how such flawed studies make it to publication and how the scientific community can combat such disinformation.

摘要

近年来,作物科学的研究进展速度前所未有,新旧作物育种技术的融合使得“转基因”——及其变体“基因修饰生物体”(GMO)——几乎过时。这是一种伪范畴,主要用于贬义地指代使用最新、最精确、最可预测的分子遗传技术。为了确保使用分子技术开发的商业化作物是安全的,并且新特性是有益的,人们花费了大量的时间、精力和精心的设计。然而,尽管取得了这些进展,人们对这些技术仍持怀疑态度,部分原因是一些“不良科学家”发表了欺诈性、设计不佳和有偏见的研究,他们的意图是污染科学文献,并在监管机构和公众中对分子遗传修饰产生不信任。我们讨论了这些有缺陷的研究是如何发表的,以及科学界如何应对这种虚假信息。

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本文引用的文献

1
Characterization of scientific studies usually cited as evidence of adverse effects of GM food/feed.
Plant Biotechnol J. 2017 Oct;15(10):1227-1234. doi: 10.1111/pbi.12798. Epub 2017 Aug 16.
2
Italian papers on genetically modified crops under investigation.
Nature. 2016 Jan 21;529(7586):268-9. doi: 10.1038/nature.2016.19183.
3
Editor in Chief of Food and Chemical Toxicology answers questions on retraction.
Food Chem Toxicol. 2014 Mar;65:394-5. doi: 10.1016/j.fct.2014.01.006. Epub 2014 Jan 6.
4
The MMR vaccine and autism: Sensation, refutation, retraction, and fraud.
Indian J Psychiatry. 2011 Apr;53(2):95-6. doi: 10.4103/0019-5545.82529.
5
Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada.
Reprod Toxicol. 2011 May;31(4):528-33. doi: 10.1016/j.reprotox.2011.02.004. Epub 2011 Feb 18.
6
Health risks of genetically modified foods.
Crit Rev Food Sci Nutr. 2009 Feb;49(2):164-75. doi: 10.1080/10408390701855993.
7
Toxins in transgenic crop byproducts may affect headwater stream ecosystems.
Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16204-8. doi: 10.1073/pnas.0707177104. Epub 2007 Oct 8.
8
Gene transfer in crop improvement.
Science. 1987 Apr 3;236(4797):48-54. doi: 10.1126/science.236.4797.48.

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