MAT-InLAB, Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, 87036, Arcavacata di Rende (CS, Italy.
School of Science and Technology Chemistry Section, University of Camerino, Via S. Agostino 1, 62032, Camerino (MC, Italy.
Chempluschem. 2020 Mar;85(3):426-440. doi: 10.1002/cplu.201900681.
Ag(I)-containing ethylcellulose (EC) films suitable as antbacterial packaging materials have been prepared and fully characterized. Different preparation methods, including the use of green casting solvents, are proposed. The Ag(I) acylpyrazolonato complexes, [Ag(Q )(L)], L=benzylimidazole (Bzim) and L=ethylimidazole (EtimH), used as active additives, display different modes of interactions with EC, depending on their structural features. A thorough investigation of the EC liquid-crystalline lyotropic phase and its changes with the introduction of silver additives, has been conducted, revealing either the inclusion of complex molecules into the inner structure of the EC matrix or their dispersion on its surface. Moreover, the bactericidal activity of the prepared Ag(I) films seems to be related to the interaction between silver additives and the polymeric EC matrix. Indeed, the EC-2b films show a particularly good performance even with a low silver content, with a relative bacterial killing of about 100 %. Tests for Ag(I) migration have been performed by using three food stimulants under two assay conditions. Low values of silver release are recorded, particularly at low concentration of silver content, in the case of all new prepared Ag(I) films.
已经制备并充分表征了适合用作抗菌包装材料的含银（I）乙基纤维素（EC）薄膜。提出了不同的制备方法，包括使用绿色铸造溶剂。用作活性添加剂的银（I）酰基吡唑啉酮配合物[Ag（Q）（L）]，L=苯并咪唑（Bzim）和 L=乙基咪唑（EtimH），根据其结构特征，与 EC 具有不同的相互作用模式。对 EC 溶致液晶相及其随银添加剂引入的变化进行了深入研究，结果表明，复合分子要么被包含在 EC 基质的内部结构中，要么被分散在其表面上。此外，所制备的 Ag（I）薄膜的杀菌活性似乎与银添加剂与聚合物 EC 基质之间的相互作用有关。实际上，即使银含量低，EC-2b 薄膜也表现出特别好的性能，相对细菌杀灭率约为 100%。通过在两种测定条件下使用三种食品刺激物进行了 Ag（I）迁移测试。在所有新制备的 Ag（I）薄膜的情况下，都记录到了银释放的低值，尤其是在银含量低的情况下。
