Amsler 网格测试在埃塞俄比亚用于检测晚期青光眼。
Amsler grid test for detection of advanced glaucoma in Ethiopia.
机构信息
Department of Ophthalmology, St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Department of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, Canada.
出版信息
PLoS One. 2020 Mar 10;15(3):e0230017. doi: 10.1371/journal.pone.0230017. eCollection 2020.
OBJECTIVE
This study was done to determine the validity of amsler grid test black on white (BOW), as well as white on black (WOB) for identifying central visual field (VF) defects in patients with advanced glaucoma.
DESIGN
Prospective study.
PARTICIPANTS
We prospectively included 100 consecutive eyes of 88 adult patients with advanced glaucoma and 100 eyes of 100 normal individuals. We used a lottery method to choose the side of the eye for the control groups.
METHODS
All participants had reliable Humphrey 10-2 Swedish Interactive Threshold Algorithm (SITA) standard VF. Both the BOW and WOB amsler grid tests were done for each group. Sensitivity, specificity, and positive and negative predictive values of the amsler grid scotoma area were calculated with the 10-2 VF as the reference standard.
RESULTS
The mean ± standard deviation (SD) of age and the 10-2 VF mean deviation (MD) of advanced glaucoma eyes were 59.8 ± 11.8 (range 34-84) years and -19.94 ± 9.8(range -34.98--0.52) respectively. Among 108 eyes with normal 10-2 VF test, 103 had a normal BOW amsler grid test and 5 had an abnormal BOW test. Among 92 eyes with an abnormal 10-2 VF test, 74 had an abnormal and 18 had normal BOW amsler grid test. Sensitivity, specificity, and positive and negative predictive values of the BOW amsler grid test were 80.4%, 95.4%, 93% and 85.1% respectively whereas that of the WOB amsler grid test were 71.7%, 95.4%, 93% and 72.8% respectively.
CONCLUSION
The sensitivity and specificity of both BOW and WOB amsler grid tests were high in detecting VF defects in advanced glaucoma.
目的
本研究旨在确定阿姆斯勒方格表黑底白格（BOW）和白底黑格（WOB）检测晚期青光眼患者中央视野（VF）缺损的有效性。
设计
前瞻性研究。
参与者
我们前瞻性纳入了 88 例晚期青光眼患者的 100 只连续眼和 100 名正常个体的 100 只眼。我们采用抽签法选择对照组的眼别。
方法
所有参与者均接受可靠的 Humphrey 10-2 瑞典交互式阈值算法（SITA）标准 VF 检查。为每组患者均进行 BOW 和 WOB 阿姆斯勒方格检查。计算阿姆斯勒方格检测出的暗点区域的敏感性、特异性、阳性预测值和阴性预测值，以 10-2 VF 作为参考标准。
结果
晚期青光眼眼的平均年龄±标准差（SD）和 10-2 VF 平均偏差（MD）分别为 59.8±11.8（范围 34-84）岁和-19.94±9.8（范围-34.98~0.52）。在 108 只正常 10-2 VF 测试眼，103 只眼的 BOW 阿姆斯勒方格测试正常，5 只眼的 BOW 阿姆斯勒方格测试异常。在 92 只异常 10-2 VF 测试眼，74 只眼的 BOW 阿姆斯勒方格测试异常，18 只眼的 BOW 阿姆斯勒方格测试正常。BOW 阿姆斯勒方格检测的敏感性、特异性、阳性预测值和阴性预测值分别为 80.4%、95.4%、93%和 85.1%，而 WOB 阿姆斯勒方格检测的敏感性、特异性、阳性预测值和阴性预测值分别为 71.7%、95.4%、93%和 72.8%。
结论
BOW 和 WOB 阿姆斯勒方格检测在检测晚期青光眼的 VF 缺损方面具有较高的敏感性和特异性。
Zotero 插件